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FOXA2 Products

(Forkhead Box A2 (FOXA2))

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This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].

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Featured FOXA2 Categories

FOXA2 Antibodies

High quality antibodies with extensive validation data.

FOXA2 ELISA Kits

Reliable ELISA kits for a wide range of species.

FOXA2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FOXA2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IP, RNAi
Validations
  • (7)
Cat. No. ABIN561301
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Application WB
Validations
  • (3)
  • (6)
Cat. No. ABIN2777512
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN185022
Quantity 100 μg
Datasheet Datasheet

Recommended FOXA2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966874
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955972
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5654407
Quantity 96 tests
Datasheet Datasheet

Recommended FOXA2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354327
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354326
Quantity 25 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398836
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FOXA2 products

Rajderkar, Mann, Panaretos, Yumoto, Li, Mishina, Ralston, Kaartinen: "Trim33 is required for appropriate development of pre-cardiogenic mesoderm." in: Developmental biology, Vol. 450, Issue 2, pp. 101-114, (2019) (PubMed).

Lee, Cho, Rickert, Li, Pulecio, Leslie, Huangfu: "FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation." in: Cell reports, Vol. 28, Issue 2, pp. 382-393.e7, (2019) (PubMed).

Huang, Guo, Li, Zhang: "Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes." in: Scientific reports, Vol. 7, pp. 40716, (2018) (PubMed).

Tomizawa, Shinozaki, Motoyoshi, Sugiyama, Yamamoto, Ishige: "Transcription Factors and Medium Suitable for Initiating the Differentiation of Human-Induced Pluripotent Stem Cells to the Hepatocyte Lineage." in: Journal of cellular biochemistry, Vol. 117, Issue 9, pp. 2001-9, (2016) (PubMed).

Vorvis, Hatziapostolou, Mahurkar-Joshi, Koutsioumpa, Williams, Donahue, Poultsides, Eibl, Iliopoulos: "Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 310, Issue 11, pp. G1124-37, (2016) (PubMed).

Yamamizu, Schlessinger, Ko: "SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1)." in: Development (Cambridge, England), Vol. 141, Issue 22, pp. 4254-66, (2014) (PubMed).

Kurtz, Peck, Fannin, Beysen, Miao, Landstreet, Ding, Turaga, Lund, Turner, Biddinger, Vickers, Sethupathy: "MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes." in: Diabetes, Vol. 63, Issue 9, pp. 3141-8, (2014) (PubMed).

Simeonov, Uppal: "Direct reprogramming of human fibroblasts to hepatocyte-like cells by synthetic modified mRNAs." in: PLoS ONE, Vol. 9, Issue 6, pp. e100134, (2014) (PubMed).

Kallas, Pook, Trei, Maimets: "SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate." in: Stem cells international, Vol. 2014, pp. 298163, (2014) (PubMed).

Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, (2013) (PubMed).

Synonyms and alternative names related to FOXA2

forkhead box A2 (foxa2), forkhead box A2 (FOXA2), forkhead box A2 L homeolog (foxa2.L), forkhead box A2 (Foxa2), ax, axl, fkd1, FOXA2, FoxA2-A, FoxA2a, HNF-3B, HNF-3b, Hnf-3b, HNF-3BETA, hnf3-beta, HNF3-beta, hnf3b, HNF3B, Hnf3b, hnf3beta, HNF3beta, ik:tdsubc_2g8, Tcf-3b, tcf3b, TCF3B, Tcf3b, tdsubc_2g8, wu:fe05g04, xbeta-1, xFD-3, xx:tdsubc_2g8

Protein level used designations for FOXA2

  • fork head transcription factor FoxA2
  • forkhead box protein A2
  • forkhead box A2
  • HNF-3-beta
  • HNF-3B
  • TCF-3B
  • hepatic nuclear factor-3-beta
  • hepatocyte nuclear factor 3, beta
  • hepatocyte nuclear factor 3-beta
  • transcription factor 3B
  • axial protein
  • etID309811.17
  • hnf3b
  • mol
  • monorail
  • HNF-3-beta-A
  • HNF3-beta homolog A
  • HNF3-beta-A
  • Hepatocyte nuclear factor 3-beta homolog A
  • fork head domain-related protein 3
  • forkhead box protein A2-A
  • xHNF3-beta-A
  • hepatocyte nuclear factor 3 beta
  • hepatocyte nuclear factor 3 beta (winged helix transcription factor)
  • hepatocyte nuclear factor-3 beta
  • hepatocyte nuclear factor-3beta
  • transcription factor Foxa2
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