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FOLR1 Products

(Folate Receptor 1 (Adult) (FOLR1))

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The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009].

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Featured FOLR1 Categories

FOLR1 Antibodies

High quality antibodies with extensive validation data.

FOLR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

FOLR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FOLR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5611335
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7267224
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN7267223
Quantity 100 μL
Datasheet Datasheet

Recommended FOLR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6955944
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955945
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN924883
Quantity 96 tests
Datasheet Datasheet

Recommended FOLR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274667
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7092684
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274666
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FOLR1 products

Taniuchi, Yawata, Tsuboi, Ueba, Saibara: "Efficient delivery of small interfering RNAs targeting particular mRNAs into pancreatic cancer cells inhibits invasiveness and metastasis of pancreatic tumors." in: Oncotarget, Vol. 10, Issue 30, pp. 2869-2886, (2019) (PubMed).

Castaño, Caviedes, Hirsch, Llanos, Iñiguez, Ronco: "Folate Transporters in Placentas from Preterm Newborns and Their Relation to Cord Blood Folate and Vitamin B12 Levels." in: PloS one, Vol. 12, Issue 1, pp. e0170389, (2017) (PubMed).

Ando, Nagata, Nihira, Suzuki, Kanda, Adachi, Kubota, Kameyama, Nakano, Ando, Yamano, Ishii, Nakai, Nakamura: "Potent Therapeutic Activity Against Peritoneal Dissemination and Malignant Ascites by the Novel Anti-Folate Receptor Alpha Antibody KHK2805." in: Translational oncology, Vol. 10, Issue 5, pp. 707-718, (2017) (PubMed).

Kameyama, Motoyama, Tanaka, Yamashita, Higashi, Arima: "Induction of mitophagy-mediated antitumor activity with folate-appended methyl-β-cyclodextrin." in: International journal of nanomedicine, Vol. 12, pp. 3433-3446, (2017) (PubMed).

Mohanty, Shah, Allender, Siddiqui, Monick, Ichi, Mania-Farnell, G McLone, Tomita, Mayanil: "Folate Receptor Alpha Upregulates Oct4, Sox2 and Klf4 and Downregulates miR-138 and miR-let-7 in Cranial Neural Crest Cells." in: Stem cells (Dayton, Ohio), (2016) (PubMed).

Yang, He, Liu, Xia, Fang, Xie, Gan, He, Tan, Jiang, Tong, Song: "Promising Nanocarriers for PEDF Gene Targeting Delivery to Cervical Cancer Cells Mediated by the Over-expressing FRα." in: Scientific reports, Vol. 6, pp. 32427, (2016) (PubMed).

Azaïs, Queniat, Bonner, Kerdraon, Tardivel, Jetpisbayeva, Frochot, Betrouni, Collinet, Mordon: "Fischer 344 Rat: A Preclinical Model for Epithelial Ovarian Cancer Folate-Targeted Therapy." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 25, Issue 7, pp. 1194-200, (2015) (PubMed).

Celik, Karaer, Turkcuoglu, Turhan, Gungoren, Taskapan, Ozyalin, Berker: "Association of folic acid receptor ? in maternal serum with neural tube defects." in: The journal of maternal-fetal & neonatal medicine, Vol. 27, Issue 11, pp. 1083-7, (2014) (PubMed).

Qi, Liu, Zhao, Zou, Zhang, Li, Wang, Li, Zou, Xia, Wang, Xing, Li, Lu, Tang, Zhou, Liu, Gui, Cai, Sun: "Quantitation of rare circulating tumor cells by folate receptor ? ligand-targeted PCR in bladder transitional cell carcinoma and its potential diagnostic significance." in: Tumour biology, Vol. 35, Issue 7, pp. 7217-23, (2014) (PubMed).

Kelemen, Brenton, Parkinson, C Whitaker, Piskorz, Csizmadi, Robson: "Conditions associated with circulating tumor-associated folate receptor 1 protein in healthy men and women." in: PLoS ONE, Vol. 9, Issue 5, pp. e96542, (2014) (PubMed).

Synonyms and alternative names related to FOLR1

folate receptor 1 (FOLR1), folate receptor 1 (adult) (folr1), folate receptor 1 (adult) L homeolog (folr1.L), folate receptor 1 (adult) (FOLR1), zgc:165502 (zgc:165502), Folate receptor alpha (folr1), folate receptor 1 (adult) (Folr1), folate receptor 1 (Folr1), folate receptor alpha (LOC100066084), folate receptor alpha (LOC100725439), FBP, fbp, FBP1, Fbp1, Folbp-1, Folbp1, FOLR, folr, folr1, FOLR1, Folr1

Protein level used designations for FOLR1

  • FR-alpha
  • KB cells FBP
  • adult folate-binding protein
  • folate binding protein
  • folate receptor alpha
  • folate receptor, adult
  • ovarian tumor-associated antigen MOv18
  • erythroid-specific folate receptor
  • membrane-bound folate binding protein
  • folate receptor 1 (adult)
  • Folate receptor alpha
  • folate binding protein 1
  • folate-binding protein 1
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