FNTA Products
(Farnesyltransferase, CAAX Box, alpha (FNTA))
Categories
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010].
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Featured FNTA Categories
FNTA Antibodies
High quality antibodies with extensive validation data.
FNTA ELISA Kits
Reliable ELISA kits for a wide range of species.
FNTA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FNTA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (3)
Cat. No.
ABIN7441346
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (5)
- (2)
Cat. No.
ABIN1882083
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN947877
Quantity
50 μg
Datasheet
Datasheet
Recommended FNTA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955698
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
- (2)
Cat. No.
ABIN1133744
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN5594906
Quantity
96 tests
Datasheet
Datasheet
Recommended FNTA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354288
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7408576
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2721272
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our FNTA products
: "A High-Fructose-High-Coconut Oil Diet Induces Dysregulating Expressions of Hippocampal Leptin and Stearoyl-CoA Desaturase, and Spatial Memory Deficits in Rats." in: Nutrients, Vol. 9, Issue 6, (2018) (PubMed).: "Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, Tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin ..." in: PLoS ONE, Vol. 9, Issue 2, pp. e89169, (2014) (PubMed).
: "Upregulation of geranylgeranyltransferase I in bronchial smooth muscle of mouse experimental asthma: its inhibition by lovastatin." in: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, Vol. 46, Issue 1, pp. 57-64, (2010) (PubMed).
: "The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling." in: Science (New York, N.Y.), Vol. 271, Issue 5252, pp. 1120-2, (1996) (PubMed).
: "cDNA cloning and expression of rat and human protein geranylgeranyltransferase type-I." in: The Journal of biological chemistry, Vol. 269, Issue 5, pp. 3175-80, (1994) (PubMed).
: "cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences." in: Genomics, Vol. 18, Issue 1, pp. 105-12, (1994) (PubMed).
: "Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases." in: Biochemistry, Vol. 32, Issue 19, pp. 5167-76, (1993) (PubMed).
Synonyms and alternative names related to FNTA
farnesyltransferase A (FTA), farnesyltransferase, CAAX box, alpha (FNTA), farnesyltransferase, CAAX box, alpha (Fnta), ATFTA, FARNESYLTRANSFERASE A, farnesyltransferase A, FARNESYLTRANSFERASE SUBUNIT A, FPTA, FTA, PFAS, PFT/PGGT-IALPHA, PGGT1A, PLP, PLURIPETALA, PTAR2Protein level used designations for FNTA
- FTase-alpha
- GGTase-I-alpha
- farnesyl-protein transferase alpha-subunit
- protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
- protein prenyltransferase alpha subunit repeat containing 2
- ras proteins prenyltransferase subunit alpha
- type I protein geranyl-geranyltransferase alpha subunit
- CAAX farnesyltransferase subunit alpha
- type I protein geranyl-geranyltransferase subunit alpha
- Farnesyltransferase, subunit alpha
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