FMR1 Products
(Fragile X Mental Retardation 1 (FMR1))
Categories
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010].
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Featured FMR1 Categories
FMR1 Antibodies
High quality antibodies with extensive validation data.
FMR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
FMR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FMR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (16)
Cat. No.
ABIN1498287
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IF, IHC (p), FACS
Validations
- (16)
Cat. No.
ABIN1491454
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (11)
Cat. No.
ABIN1491292
Quantity
100 μL
Datasheet
Datasheet
Recommended FMR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955988
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974787
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5654421
Quantity
96 tests
Datasheet
Datasheet
Recommended FMR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354256
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354258
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7409242
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FMR1 products
: "Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain." in: Molecular psychiatry, (2018) (PubMed).: "A novel role of fragile X mental retardation protein in pre-mRNA alternative splicing through RNA-binding protein 14." in: Neuroscience, Vol. 349, pp. 64-75, (2018) (PubMed).
: "RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC." in: PLoS genetics, Vol. 12, Issue 9, pp. e1006306, (2017) (PubMed).
: "Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP." in: eNeuro, Vol. 3, Issue 6, (2017) (PubMed).
: "Comparison of Equivalence between Two Commercially Available S499-Phosphorylated FMRP Antibodies in Mice." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143134, (2016) (PubMed).
: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." in: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).
: "FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity." in: PLoS ONE, Vol. 9, Issue 5, pp. e96956, (2015) (PubMed).
: "Profiling Chlamydomonas metabolism under dark, anoxic H2-producing conditions using a combined proteomic, transcriptomic, and metabolomic approach." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5431-51, (2014) (PubMed).
: "Fragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virus." in: Nature communications, Vol. 5, pp. 3259, (2014) (PubMed).
: "A quantitative homogeneous assay for fragile X mental retardation 1 protein." in: Journal of neurodevelopmental disorders, Vol. 5, Issue 1, pp. 8, (2013) (PubMed).
Synonyms and alternative names related to FMR1
CG6203 gene product from transcript CG6203-RC (Fmr1), fragile X mental retardation 1 (FMR1), fragile X mental retardation 1 (Fmr1), fragile X mental retardation 1 (fmr1), fragile X mental retardation syndrome 1 (Fmr1), AT24755, BcDNA:GM08679, CG6203, cg6203, dFMR, dfmr, dFMR1, dFmr1, dfmr1, dFMRP, dFmrp, dFXR, dfxr, dFXR1, dfxr1, dFXRP, Dmel\\CG6203, dmfr1, EP(3)3517, FMR, fmr, Fmr-1, FMR1, fmr1, FMRP, FMRp, Fmrp, FRAXA, FXR, POF, POF1, zFMR1Protein level used designations for FMR1
- CG6203-PA
- CG6203-PB
- CG6203-PC
- CG6203-PD
- CG6203-PE
- CG6203-PF
- CG6203-PG
- CG6203-PH
- CG6203-PI
- Fmr1-PA
- Fmr1-PB
- Fmr1-PC
- Fmr1-PD
- Fmr1-PE
- Fmr1-PF
- Fmr1-PG
- Fmr1-PH
- Fmr1-PI
- Fragile-X mental retardation protein
- Fragile-X-related
- dFmr1
- drosophila fragile X mental retardation protein
- fragile X
- fragile X mental retardation
- fragile X mental retardation 1
- fragile X mental retardation gene
- fragile X mental retardation protein
- fragile X protein
- fragile X related protein
- fragile X-related
- fragile x related
- fragile-X
- fragile X mental retardation protein 1
- fragile X mental retardation protein 1 homolog
- fragile X mental retardation syndrome 1 homolog
- fragile X mental retardation-1 protein
- protein FMR-1
- ragile X mental retardation protein
- fragile X mental retardation 1 protein
- FMRP
- mFmr1p
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