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FLT4 Products

(Fms-Related Tyrosine Kinase 4 (FLT4))
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008].

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Featured FLT4 Categories

FLT4 Antibodies

High quality antibodies with extensive validation data.

FLT4 ELISA Kits

Reliable ELISA kits for a wide range of species.

FLT4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FLT4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (5)
  • (5)
Cat. No. ABIN1882290
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
  • (7)
Cat. No. ABIN5693136
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN6140699
Quantity 100 μL
Datasheet Datasheet

Recommended FLT4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955941
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971114
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955942
Quantity 96 tests
Datasheet Datasheet

Recommended FLT4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275832
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275839
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275840
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FLT4 products

Zarjou, Black, Bolisetty, Traylor, Bowhay, Zhang, Harris, Agarwal: "Dynamic signature of lymphangiogenesis during acute kidney injury and chronic kidney disease." in: Laboratory investigation; a journal of technical methods and pathology, (2019) (PubMed).

Norman, Gower, Chen, Fine: "Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216795, (2019) (PubMed).

Reed, Wang, Sonett, Chen, Yang, Li, Aradi, Jakus, DArmiento, Hancock, Kahn: "Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage." in: The Journal of clinical investigation, Vol. 129, Issue 6, pp. 2514-2526, (2019) (PubMed).

Durré, Morfoisse, Erpicum, Ebroin, Blacher, García-Caballero, Deroanne, Louis, Balsat, Van de Velde, Kaijalainen, Kridelka, Engelholm, Struman, Alitalo, Behrendt, Paupert, Noel: "uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis." in: Nature communications, Vol. 9, Issue 1, pp. 5178, (2019) (PubMed).

Deng, Gui, Kim, Xie, Chen, Li, He, Chen, Chen, Luo, Lu, Xie, Churchill, Xu, Zhou, Wu, Yu, John, Hirayasu, Nguyen, Liu, Huang, Li, Deng, Tang, Sadek, Zhang, Huang, Zou, Chen, Zhu, Arase, Xia, Jiang et al.: "LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. ..." in: Nature, Vol. 562, Issue 7728, pp. 605-609, (2019) (PubMed).

Jang, Choi, Park, Park, Choe, Kim, Kim, Lee, Hirashima, Kubota, Park, Cheng, Nagy, Park, Alitalo, Shong, Koh: "VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit in normal state and during goitrogenesis." in: EMBO molecular medicine, Vol. 9, Issue 6, pp. 750-769, (2018) (PubMed).

Song, Park, Ko, Park, Yoon, Kim, Kim, Kim, Lee, Prockop, Oh: "Mesenchymal Stromal Cells Inhibit Inflammatory Lymphangiogenesis in the Cornea by Suppressing Macrophage in a TSG-6-Dependent Manner." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 26, Issue 1, pp. 162-172, (2018) (PubMed).

Zhang, Ulvmar, Stanczuk, Martinez-Corral, Frye, Alitalo, Mäkinen: "Heterogeneity in VEGFR3 levels drives lymphatic vessel hyperplasia through cell-autonomous and non-cell-autonomous mechanisms." in: Nature communications, Vol. 9, Issue 1, pp. 1296, (2018) (PubMed).

Frye, Taddei, Dierkes, Martinez-Corral, Fielden, Ortsäter, Kazenwadel, Calado, Ostergaard, Salminen, He, Harvey, Kiefer, Mäkinen: "Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program." in: Nature communications, Vol. 9, Issue 1, pp. 1511, (2018) (PubMed).

Thomson, van de Pavert, Stakenborg, Labeeuw, Matteoli, Mowat, Nibbs: "Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 1, pp. 215-229, (2018) (PubMed).

Synonyms and alternative names related to FLT4

fms related tyrosine kinase 4 (FLT4), FMS-like tyrosine kinase 4 (Flt4), fms-related tyrosine kinase 4 (Flt4), fms-related tyrosine kinase 4 (flt4), AI323512, cb1059, Chy, Flt-4, FLT41, LMPH1A, PCL, VEGFR-3, VEGFR3, Vegfr3

Protein level used designations for FLT4

  • FLT-4
  • VEGFR-3
  • fms-like tyrosine kinase 4
  • soluble VEGFR3 variant 1
  • soluble VEGFR3 variant 2
  • soluble VEGFR3 variant 3
  • tyrosine-protein kinase receptor FLT4
  • vascular endothelial growth factor receptor 3
  • chylous ascites
  • receptor protein tyrosine kinase
  • vascular endothelial growth factor receptor-3
  • FMS-like tyrosine kinase 4
  • tyrosine kinase VEGFR-3
  • VEGFR3
  • expando
  • receptor tyrosine kinase Flt4
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