FLNC Products
(Filamin C, gamma (FLNC))
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This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured FLNC Categories
FLNC Antibodies
High quality antibodies with extensive validation data.
FLNC ELISA Kits
Reliable ELISA kits for a wide range of species.
FLNC Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FLNC Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441958
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (2)
Cat. No.
ABIN560923
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7435937
Quantity
100 μL
Datasheet
Datasheet
Recommended FLNC ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955916
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN776808
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rabbit
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN774853
Quantity
96 tests
Datasheet
Datasheet
Recommended FLNC Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354206
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505105
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7413877
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FLNC products
: "De novo mutations in FLNC leading to early-onset restrictive cardiomyopathy and congenital myopathy." in: Human mutation, Vol. 39, Issue 9, pp. 1161-1172, (2018) (PubMed).: "Congenital dilated cardiomyopathy caused by biallelic mutations in Filamin C." in: European journal of human genetics : EJHG, Vol. 24, Issue 12, pp. 1792-1796, (2016) (PubMed).
: "FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." in: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).
: "Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy." in: Nature communications, Vol. 5, pp. 5326, (2014) (PubMed).
: "Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease." in: EMBO molecular medicine, Vol. 5, Issue 2, pp. 210-20, (2013) (PubMed).
: "Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 18, Issue 9, pp. 810-22, (2013) (PubMed).
: "Identification of a novel protein (VBP-1) binding to the von Hippel-Lindau (VHL) tumor suppressor gene product." in: Cancer research, Vol. 56, Issue 13, pp. 2881-5, (1996) (PubMed).
: "Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 7, pp. 3461-70, (1995) (PubMed).
: "Different temporal patterns of expression result in the same type, amount, and distribution of filamin (ABP) in cardiac and skeletal myofibrils." in: Cell motility and the cytoskeleton, Vol. 27, Issue 3, pp. 248-61, (1994) (PubMed).
: "The exon-intron organization of the human X-linked gene (FLN1) encoding actin-binding protein 280." in: Genomics, Vol. 21, Issue 1, pp. 71-6, (1994) (PubMed).
Synonyms and alternative names related to FLNC
filamin C (FLNC), filamin C L homeolog (flnc.L), filamin C (flnc), filamin C, gamma (Flnc), filamin C (Flnc), 1110055E19Rik, ABP-280, ABP280A, ABPA, ABPL, Fln2, FLN2, MFM5, MPD4Protein level used designations for FLNC
- filamin C, gamma (actin binding protein 280)
- gamma filamin
- filamin C, gamma
- filamin-C-like
- ABP-280-like protein
- ABP-L
- FLN-C
- actin binding protein 280
- actin-binding protein 280
- actin-binding-like protein
- filamin, gamma
- filamin-2
- filamin-C
- gamma-filamin
- ABP-L, gamma filamin
- filamin 2
- 260kDa actin-binding protein
- cgABP260 actin-binding domain
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