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FLNB Products

(Filamin B, beta (FLNB))
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3\; boomerang dysplasia\; autosomal dominant Larsen syndrome\; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Nov 2009].

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Featured FLNB Categories

FLNB Antibodies

High quality antibodies with extensive validation data.

FLNB ELISA Kits

Reliable ELISA kits for a wide range of species.

FLNB Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FLNB Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (7)
Cat. No. ABIN7260435
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN2854971
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (8)
Cat. No. ABIN1679857
Quantity 100 μg
Datasheet Datasheet

Recommended FLNB ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (4)
Cat. No. ABIN6574321
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966827
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN776807
Quantity 96 tests
Datasheet Datasheet

Recommended FLNB Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354204
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7398248
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414777
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our FLNB products

Thompson, Shah, Ntranos, Van Gool, Atkinson, Bhushan: "Targeted Elimination of Senescent Beta Cells Prevents Type 1 Diabetes." in: Cell metabolism, Vol. 29, Issue 5, pp. 1045-1060.e10, (2019) (PubMed).

Thompson, Shah, Apostolopolou, Bhushan: "BET Proteins Are Required for Transcriptional Activation of the Senescent Islet Cell Secretome in Type 1 Diabetes." in: International journal of molecular sciences, Vol. 20, Issue 19, (2019) (PubMed).

Artym, Swatkoski, Matsumoto, Campbell, Petrie, Dimitriadis, Li, Mueller, Bugge, Gucek, Yamada: "Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network." in: The Journal of cell biology, Vol. 208, Issue 3, pp. 331-50, (2015) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Takafuta, Wu, Murphy, Shapiro: "Human beta-filamin is a new protein that interacts with the cytoplasmic tail of glycoprotein Ibalpha." in: The Journal of biological chemistry, Vol. 273, Issue 28, pp. 17531-8, (1998) (PubMed).

Synonyms and alternative names related to FLNB

filamin B (FLNB), filamin B (Flnb), filamin, beta (Flnb), ABP-278, ABP-280, AL024016, AOI, FH1, FLN-B, FLN1L, LRS1, SCT, TABP, TAP

Protein level used designations for FLNB

  • ABP-280 homolog
  • Larsen syndrome 1 (autosomal dominant)
  • actin binding protein 278
  • actin-binding-like protein
  • beta-filamin
  • filamin homolog 1
  • filamin-3
  • filamin-B
  • thyroid autoantigen
  • filamin B, beta (actin binding protein 278)
  • retina filamin
  • filamin B, beta
  • filamin-B-like
  • filamin, beta
  • ABP-280-like protein
  • FLN-B
  • filamin B beta
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