FKBP5 Products
(FK506 Binding Protein 5 (FKBP5))
Categories
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].
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Featured FKBP5 Categories
FKBP5 Antibodies
High quality antibodies with extensive validation data.
FKBP5 ELISA Kits
Reliable ELISA kits for a wide range of species.
FKBP5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FKBP5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
- (6)
Cat. No.
ABIN515669
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (6)
Cat. No.
ABIN7260887
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (7)
Cat. No.
ABIN1679852
Quantity
100 μg
Datasheet
Datasheet
Recommended FKBP5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955923
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955924
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882891
Quantity
96 tests
Datasheet
Datasheet
Recommended FKBP5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1354130
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122977
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7400387
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FKBP5 products
: "Endothelial glucocorticoid receptor promoter methylation according to dexamethasone sensitivity." in: Journal of molecular endocrinology, (2015) (PubMed).: "FKBP51 employs both scaffold and isomerase functions to promote NF-?B activation in melanoma." in: Nucleic acids research, Vol. 43, Issue 14, pp. 6983-93, (2015) (PubMed).
: "Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients." in: Pigment cell & melanoma research, Vol. 28, Issue 4, pp. 442-52, (2015) (PubMed).
: "FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells." in: Archives of medical science : AMS, Vol. 11, Issue 5, pp. 1074-80, (2015) (PubMed).
: "FKBP51 increases the tumour-promoter potential of TGF-beta." in: Clinical and translational medicine, Vol. 3, Issue 1, pp. 1, (2014) (PubMed).
: "FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential." in: Cell death & disease, Vol. 4, pp. e578, (2013) (PubMed).
: "Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. ..." in: PLoS ONE, Vol. 7, Issue 11, pp. e48385, (2012) (PubMed).
: "Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent." in: Journal of translational medicine, Vol. 9, pp. 8, (2011) (PubMed).
Synonyms and alternative names related to FKBP5
FK506 binding protein 5 (FKBP5), FK506 binding protein 5 (fkbp5), FK506 binding protein 5 (Fkbp5), AIG6, D17Ertd592e, Dit1, FKBP-5, FKBP5, FKBP51, FKBP54, P54, PPIase, Ptg-10, si:zc263a23.8, wu:fc31g11, wu:fl87b03, zgc:64082Protein level used designations for FKBP5
- FK506 binding protein 5
- FK506-binding protein 5
- PPIase FKBP5
- peptidyl-prolyl cis-trans isomerase FKBP5
- rotamase
- 51 kDa FK506-binding protein 5
- 51 kDa FKBP
- 54 kDa progesterone receptor-associated immunophilin
- FF1 antigen
- FKBP-5
- FKBP-51
- HSP90-binding immunophilin
- T-cell FK506-binding protein
- androgen-regulated protein 6
- peptidylprolyl cis-trans isomerase
- 51 kDa FK506-binding protein
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