Fibulin 5 Products
(Fibulin 5 (FBLN5))
Categories
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008].
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Featured Fibulin 5 Categories
Fibulin 5 Antibodies
High quality antibodies with extensive validation data.
Fibulin 5 ELISA Kits
Reliable ELISA kits for a wide range of species.
Fibulin 5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Fibulin 5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN728473
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7438958
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
- (2)
Cat. No.
ABIN969131
Quantity
100 μL
Datasheet
Datasheet
Recommended Fibulin 5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955903
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966819
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966820
Quantity
96 tests
Datasheet
Datasheet
Recommended Fibulin 5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2752787
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2721183
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7404167
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Fibulin 5 products
: "PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 102, pp. 70-84, (2022) (PubMed).: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." in: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).
: "Fibulin-5: a novel biomarker for evaluating severity and predicting prognosis in patients with acute intracerebral haemorrhage." in: European journal of neurology, Vol. 23, Issue 7, pp. 1195-201, (2016) (PubMed).
: "Overexpression of Fibulin-5 Attenuates Ischemia/Reperfusion Injury After Middle Cerebral Artery Occlusion in Rats." in: Molecular neurobiology, (2015) (PubMed).
: "LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis." in: Matrix biology : journal of the International Society for Matrix Biology, Vol. 34, pp. 114-23, (2014) (PubMed).
: "Fibulins 3 and 5 antagonize tumor angiogenesis in vivo." in: Cancer research, Vol. 66, Issue 5, pp. 2621-9, (2006) (PubMed).
: "The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis." in: Plant physiology, Vol. 138, Issue 3, pp. 1637-43, (2005) (PubMed).
: "Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis." in: The British journal of dermatology, Vol. 153, Issue 3, pp. 607-12, (2005) (PubMed).
: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).
Synonyms and alternative names related to Fibulin 5
fibulin 5 (fbln5), fibulin 5 (FBLN5), fibulin 5 (Fbln5), A55, ADCL2, ARCL1A, ARMD3, DANCE, DKFZp469K0327, EVEC, FBLN5, FIBL-5, Fibulin-5, MGC108414, UP50, zgc:103575Protein level used designations for Fibulin 5
- fibulin-5
- fibulin 5
- fibulin-5-like
- developmental arteries and neural crest EGF-like protein
- urine p50 protein
- FIBL-5
- EVEC
- dance
- embryonic vascular EGF repeat-containing protein
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