Fibroblast Growth Factor Receptor Products
(Fibroblast Growth Factor Receptor (FGFR))
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Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol- 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by ubiquitination, internalization and degradation (By similarity).
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Featured Fibroblast Growth Factor Receptor Categories
Fibroblast Growth Factor Receptor Antibodies
High quality antibodies with extensive validation data.
Fibroblast Growth Factor Receptor ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended Fibroblast Growth Factor Receptor Antibodies
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Recommended Fibroblast Growth Factor Receptor ELISA Kits
Product
Reactivity
Analytical Method
Validations
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Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN778747
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Goat
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN989383
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN989385
Quantity
96 tests
Datasheet
Datasheet
Recommended Fibroblast Growth Factor Receptor Proteins
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Sea Squirt
Source
Yeast
Validations
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ABIN1628579
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to Fibroblast Growth Factor Receptor
heartless (htl), fibroblast growth factor receptor 1 L homeolog (fgfr1.L), fibroblast growth factor receptor (FGFR), fibroblast growth factor receptor 1 S homeolog (fgfr1.S), fibroblast growth factor receptor (fgfr), fibroblast growth factor receptor 1 (FGFR1), fibroblast growth factor receptor 1 (fgfr1), fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L), basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849), ach, bfgfr, cd331, cd333, cek, cek2, CG7223, CT22273, CT39172, DFGF-R1, DFGF-R2, DFR-1, Dfr-1, DFR1, Dfr1, DFR1/DFGF-R2, Dmel\\CG7223, DmHD-38, DPR3, Dtk1, dtk1, DTRK(FR1), EMS2, FGF-R2, fgfbr, FGFR, fgfr, fgfr-1, fgfr-3, fgfr1, FGFR2, flg, FLG-1, flt-2, flt2, FR1, Fr1, hbgfr, HD-38, hsfgfr3ex, Htl, HTL/FGFR1, i79, i100, i150, j372, jtk4, kal2, n-sam, ogd, Tk1, x1fgfr, X1FGFR, XFGFR-1, xfgfr1, XFGFRA2Protein level used designations for Fibroblast Growth Factor Receptor
- CG7223-PA
- CG7223-PB
- CG7223-PC
- FGF receptor
- fibroblast growth factor receptor
- fibroblast growth factor receptor 1
- htl-PA
- htl-PB
- htl-PC
- FGFR-1
- fibroblast growth factor receptor-1
- fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- ibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome)
- basic fibroblast growth factor receptor 1
- basic fibroblast growth factor receptor 1-like
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