Fibrillarin Products
(Fibrillarin (FBL))
Categories
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008].
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Featured Fibrillarin Categories
Fibrillarin Antibodies
High quality antibodies with extensive validation data.
Fibrillarin ELISA Kits
Reliable ELISA kits for a wide range of species.
Fibrillarin Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Fibrillarin Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IP, ICC
Validations
- (5)
Cat. No.
ABIN2855179
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (5)
Cat. No.
ABIN6140494
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN7267175
Quantity
100 μL
Datasheet
Datasheet
Recommended Fibrillarin ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966723
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative
Validations
Cat. No.
ABIN776788
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rabbit
Analytical Method
Quantitative
Validations
Cat. No.
ABIN774833
Quantity
96 tests
Datasheet
Datasheet
Recommended Fibrillarin Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122909
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1778236
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419130
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Fibrillarin products
: "Giant Endoplasmic Reticulum vesicles (GERVs), a novel model membrane tool." in: Scientific reports, Vol. 10, Issue 1, pp. 3100, (2020) (PubMed).: "SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation." in: Nature structural & molecular biology, Vol. 25, Issue 11, pp. 1035-1046, (2019) (PubMed).
: "Small nucleoli are a cellular hallmark of longevity." in: Nature communications, Vol. 8, pp. 16083, (2018) (PubMed).
: "The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis." in: Oncotarget, Vol. 7, Issue 37, pp. 59519-59534, (2018) (PubMed).
: "Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance." in: Nature communications, Vol. 9, Issue 1, pp. 3607, (2018) (PubMed).
: "Nucleolar expansion and elevated protein translation in premature aging." in: Nature communications, Vol. 8, Issue 1, pp. 328, (2017) (PubMed).
: "Characterization of Aes nuclear foci in colorectal cancer cells." in: Journal of biochemistry, Vol. 159, Issue 1, pp. 133-40, (2016) (PubMed).
: "Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA." in: eLife, Vol. 5, (2016) (PubMed).
: "The arrangement of Brachypodium distachyon chromosomes in interphase nuclei." in: Journal of experimental botany, Vol. 67, Issue 18, pp. 5571-5583, (2016) (PubMed).
: "Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells." in: Cancer cell, Vol. 29, Issue 6, pp. 859-73, (2016) (PubMed).
Synonyms and alternative names related to Fibrillarin
fibrillarin (FBL), fibrillarin (fbl), fibrillarin (Fbl), Fibrillarin (Fib), fibrillarin (fib1), putative fibrillarin (LMJF_19_0100), fibrillarin S homeolog (fbl.S), AL022665, CG9888, Dmel\\CG9888, FBL, fbl, FIB, fib, Fibri, FLRN, GCR-6, GCR6, MGC76139, Pen59C5, pen59C5, RNU3IP1, wu:fb37g12, zgc:56145, zgc:77130Protein level used designations for Fibrillarin
- 34 kDa nucleolar scleroderma antigen
- 34-kD nucleolar scleroderma antigen
- RNA, U3 small nucleolar interacting protein 1
- rRNA 2'-O-methyltransferase fibrillarin
- fb37g12
- nucleolar protein 1
- fibrillarin
- CG9888-PA
- Fib-PA
- FIB
- histone-glutamine methyltransferase
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