FHL1 Products
(Four and A Half LIM Domains 1 (FHL1))
Categories
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.[provided by RefSeq, Nov 2009].
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Featured FHL1 Categories
FHL1 Antibodies
High quality antibodies with extensive validation data.
FHL1 ELISA Kits
Reliable ELISA kits for a wide range of species.
FHL1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FHL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (6)
Cat. No.
ABIN560899
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IC
Validations
- (2)
- (1)
Cat. No.
ABIN7306298
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
Application
WB, IHC
Validations
- (12)
- (4)
Cat. No.
ABIN2775759
Quantity
100 μL
Datasheet
Datasheet
Recommended FHL1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955987
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882885
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1133659
Quantity
96 tests
Datasheet
Datasheet
Recommended FHL1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354072
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354074
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2721133
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our FHL1 products
: "FHL1 is a major host factor for chikungunya virus infection. ..." in: Nature, Vol. 574, Issue 7777, pp. 259-263, (2019) (PubMed).: "Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology." in: Neuromuscular disorders : NMD, Vol. 27, Issue 4, pp. 338-351, (2017) (PubMed).
: "Exome Sequencing Identified a Splice Site Mutation in FHL1 that Causes Uruguay Syndrome, an X-Linked Disorder With Skeletal Muscle Hypertrophy and Premature Cardiac Death." in: Circulation. Cardiovascular genetics, Vol. 9, Issue 2, pp. 130-5, (2016) (PubMed).
: "Fhl1 W122S causes loss of protein function and late-onset mild myopathy." in: Human molecular genetics, Vol. 24, Issue 3, pp. 714-26, (2015) (PubMed).
: "Development of autoantibodies against muscle-specific FHL1 in severe inflammatory myopathies. ..." in: The Journal of clinical investigation, Vol. 125, Issue 12, pp. 4612-24, (2015) (PubMed).
: "Atractylenolide I-mediated Notch pathway inhibition attenuates gastric cancer stem cell traits." in: Biochemical and biophysical research communications, Vol. 450, Issue 1, pp. 353-9, (2014) (PubMed).
: "HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress." in: Nature communications, Vol. 5, pp. 3430, (2014) (PubMed).
: "A case of adult-onset reducing body myopathy presenting a novel clinical feature, asymmetrical involvement of the sternocleidomastoid and trapezius muscles." in: Journal of the neurological sciences, Vol. 343, Issue 1-2, pp. 206-10, (2014) (PubMed).
: "High prevalence of epigenetic inactivation of the human four and a half LIM domains 1 gene in human oral cancer." in: International journal of oncology, Vol. 42, Issue 1, pp. 141-50, (2012) (PubMed).
: "Identification of an FHL1 protein complex containing ACTN1, ACTN4, and PDLIM1 using affinity purifications and MS-based protein-protein interaction analysis." in: Molecular bioSystems, Vol. 7, Issue 4, pp. 1185-96, (2011) (PubMed).
Synonyms and alternative names related to FHL1
four and a half LIM domains 1 (fhl1), four and a half LIM domains 1 (FHL1), four and a half LIM domains 1a (fhl1a), Four and a half LIM domains protein 1 (fhl1), four and a half LIM domains 1 S homeolog (fhl1.S), four and a half LIM domains 1 (Fhl1), DKFZp468O1927, fhl, FHL-1, fhl1, FHL1, Fhl1, FHL1A, FHL1B, fhla, FLH1A, KYOT, KyoT, MGC89165, SLIM, SLIM-1, SLIM1, SLIMMER, XMPMA, zgc:92025Protein level used designations for FHL1
- four and a half LIM domains 1
- four and a half LIM domains protein 1-like
- four and a half LIM domains a
- four and a half LIM domains protein 1
- Four and a half LIM domains protein 1
- four and a half lim domains protein 1
- LIM protein SLIMMER
- four-and-a-half Lin11, Isl-1 and Mec-3 domains 1
- skeletal muscle LIM-protein 1
- FHL-1
- RAM14-1
- RBP-associated molecule 14-1
- SLIM
- SLIM-1
- four and a half LIM domains 1 protein
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