FGG Products
(Fibrinogen gamma Chain (FGG))
Categories
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured FGG Categories
FGG Antibodies
High quality antibodies with extensive validation data.
FGG ELISA Kits
Reliable ELISA kits for a wide range of species.
FGG Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FGG Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, ELISA, ICC, FACS
Validations
- (2)
- (6)
Cat. No.
ABIN969142
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7434950
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7437560
Quantity
100 μL
Datasheet
Datasheet
Recommended FGG ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6955785
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6974498
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966744
Quantity
96 tests
Datasheet
Datasheet
Recommended FGG Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1354052
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122911
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Cow
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7504915
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FGG products
: "iTRAQ-Based Quantitative Proteomics Reveals the New Evidence Base for Traumatic Brain Injury Treated with Targeted Temperature Management." in: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, Vol. 15, Issue 1, pp. 216-232, (2019) (PubMed).: "The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology." in: Alzheimer's research & therapy, Vol. 9, Issue 1, pp. 31, (2018) (PubMed).
: "Label-Free Quantitative Proteomics Reveals Differences in Molecular Mechanism of Atherosclerosis Related and Non-Related to Chronic Kidney Disease." in: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).
: "Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice." in: Life sciences, Vol. 167, pp. 57-66, (2016) (PubMed).
: "The human liver-specific proteome defined by transcriptomics and antibody-based profiling." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 7, pp. 2901-14, (2014) (PubMed).
: "Differences of circulating inflammatory markers between large- and small vessel disease in patients with acute ischemic stroke." in: International journal of medical sciences, Vol. 10, Issue 10, pp. 1399-405, (2013) (PubMed).
: "Proteomic analysis of cerebrospinal fluid from obese women with idiopathic intracranial hypertension: a new approach for identifying new candidates in the pathogenesis of obesity." in: Journal of neuroendocrinology, Vol. 24, Issue 6, pp. 944-52, (2012) (PubMed).
: "Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease." in: American journal of respiratory and critical care medicine, Vol. 183, Issue 12, pp. 1633-43, (2011) (PubMed).
: "The pleiotropic role of the fibrinogen gamma' chain in hemostasis." in: Blood, Vol. 114, Issue 19, pp. 3994-4001, (2009) (PubMed).
: "Impaired protofibril formation in fibrinogen gamma N308K is due to altered D:D and "A:a" interactions." in: Biochemistry, Vol. 48, Issue 36, pp. 8656-63, (2009) (PubMed).
Synonyms and alternative names related to FGG
fibrinogen gamma chain (FGG), coagulation factor XII (Hageman factor) (F12), fibrinogen gamma chain (fgg), fibrinogen gamma chain (Fgg), fibrinogen gamma chain L homeolog (fgg.L), fibrinogen gamma chain (CpipJ_CPIJ006387), fibrinogen gamma chain (CpipJ_CPIJ010087), 3010002H13Rik, AI256424, fb60h05, fb62e01, FGG, fibrinogen, FXII, HAF, LOC100220680, wu:fb60h05, wu:fb62e01, zgc:56023Protein level used designations for FGG
- fibrinogen, gamma polypeptide
- coagulation factor XII
- factor XII
- hageman factor
- fibrinogen gamma polypeptide
- gamma-fibrinogen
- fibrinogen gamma-chain
- fibrinogen, gamma chain
- gamma chain
- gamma polypeptide
- fibrinogen gamma chain
- fibrinogen gamma-B chain
- gamma'
- fibrinogen gamma chain-like
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