FGFR1b antibody (Ectodomain, Pro23)
FGFR1b
Reactivity: Human
IP, IHC, WB
Host: Mouse
Monoclonal
M17A3
unconjugated
-
- Target
- FGFR1b (Fibroblast Growth Factor Receptor 1 beta (FGFR1b))
- Binding Specificity
- Ectodomain, Pro23
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Application
- Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
- Specificity
- Reacts with human Fibroblast Growth Factor Receptor 1 beta (FGFR1β). Epitope is undetermined but presumed to be near junction of the common FGFr1 NH2-terminus and NH2-terminus of Ig loop II.
- Purification
- Purified (protein G)
- Immunogen
- Recombinant human ectodomain of FGFr1beta expressed in E. coli beginning with pro23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.
- Clone
- M17A3
- Isotype
- IgG2b
-
- Application Notes
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB(1 μg/mL) - Restrictions
- For Research Use only
-
- Buffer
- PBS, pH 7.4.
- Handling Advice
- Dilute in PBS or medium that is identical to that used in the assay system.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- FGFR1b (Fibroblast Growth Factor Receptor 1 beta (FGFR1b))
- Background
-
Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.
FGFR-1 Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1 Fms-like tyrosine kinase 2, FLT-2 N-sam Proto-oncogene c-Fgr CD_antigen : CD331 CEK FLG HH2 OGD KAL2 HBGFR HRTFDS Gene name : FGFR1 - Gene ID
- 2260
- UniProt
- P11362
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