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FGFR1 Proteins

(Fibroblast Growth Factor Receptor 1 (FGFR1))

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].

recommended

FGFR1 Protein (AA 22-374) (His-Avi Tag) (ABIN7274633)

FGFR1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

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FGFR1 Origin: Human Host: Insect Cells Recombinant > 90 % by SDS-PAGE Active

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recommended

FGFR1 Protein (AA 22-376) (His tag) (ABIN7538233)

FGFR1 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

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FGFR1 Proteins by Origin

Find FGFR1 Proteins for a variety of species such as anti-Human FGFR1, anti-Mouse FGFR1, anti-Rat FGFR1. The species listed below are among those available. Click on a link to go to the corresponding products.

FGFR1 Proteins by Source

Here you will find FGFR1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

FGFR1 Proteins by Protein Type

Here you can find FGFR1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

FGFR1 Proteins by Application

Find FGFR1 Proteins validated for a specific application such as ELISA, WB, AbP, SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

FGFR1 Proteins by Biological Activity

Find FGFR1 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular FGFR1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

FGFR1 Protein (AA 22-374) (His-Avi Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7274633

Quantity 100 μg

Datasheet Datasheet

FGFR1 Protein (Dimer, glycosylated, Soluble) (Fc Tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN1589526

Quantity 10 μg

Datasheet Datasheet

FGFR1 Protein (AA 22-376) (His tag)

Reactivity Human

Source Mammalian Cells

Validations

Cat. No. ABIN7538233

Quantity 50 μg

Datasheet Datasheet

FGFR1 Protein (AA 624-822) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7122955

Quantity 50 μg

Datasheet Datasheet

FGFR1 Protein (AA 31-150) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1354029

Quantity 10 μg

Datasheet Datasheet

FGFR1 Protein (AA 303-408) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1354031

Quantity 10 μg

Datasheet Datasheet

FGFR1 Protein (AA 22-376) (His tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN5854969

Quantity 50 μg

Datasheet Datasheet

FGFR1 Protein (AA 1-731) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1354028

Quantity 25 μg

Datasheet Datasheet

FGFR1 Protein (GST tag,His tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN7317102

Quantity 50 μg

Datasheet Datasheet

FGFR1 Protein (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7320381

Quantity 100 μg

Datasheet Datasheet

FGFR1 Protein (Fc Tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7320382

Quantity 100 μg

Datasheet Datasheet

FGFR1 Protein (GST tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN5508930

Quantity 10 μg

Datasheet Datasheet

FGFR1 Protein (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7394825

Quantity 100 μg

Datasheet Datasheet

FGFR1 Protein (AA 236-362) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7394822

Quantity 100 μg

Datasheet Datasheet

FGFR1 Protein (Fc Tag,His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7534826

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our FGFR1 Proteins

Lohr, Mock, Beckhove, Herold-Mende: "Endothelial Cells Derived from Non-malignant Tissues Are of Limited Value as Models for Brain Tumor Vasculature." in: Anticancer research, Vol. 35, Issue 5, pp. 2681-90, (2015) (PubMed).

Kim, Al-Hilal, Chung, Kim, Ryu, Son, Byun: "Antiangiogenic and anticancer effect of an orally active low molecular weight heparin conjugates and its application to lung cancer chemoprevention." in: Journal of controlled release : official journal of the Controlled Release Society, Vol. 199, pp. 122-31, (2015) (PubMed).

Teodorczyk, Kleber, Wollny, Sefrin, Aykut, Mateos, Herhaus, Sancho-Martinez, Hill, Gieffers, Sykora, Weichert, Eisen, Trumpp, Sprick, Bergmann, Welsch, Martin-Villalba: "CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma." in: Cell death and differentiation, Vol. 22, Issue 7, pp. 1192-202, (2015) (PubMed).

Tsimafeyeu, Zaveleva, Stepanova, Low: "OM-RCA-01, a novel humanized monoclonal antibody targeting fibroblast growth factor receptor 1, in renal cell carcinoma model." in: Investigational new drugs, Vol. 31, Issue 6, pp. 1436-43, (2013) (PubMed).

Aliases for FGFR1 Proteins

fibroblast growth factor receptor (FGFR) Proteins
fibroblast growth factor receptor (fgfr) Proteins
fibroblast growth factor receptor 1 S homeolog (fgfr1.S) Proteins
basic fibroblast growth factor receptor 1 (CpipJ_CPIJ005849) Proteins
heartless (htl) Proteins
fibroblast growth factor receptor 1 (fgfr1) Proteins
fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog (fgfr3.L) Proteins
fibroblast growth factor receptor 1 (FGFR1) Proteins
fibroblast growth factor receptor 1 (Fgfr1) Proteins
Fibroblast growth factor receptor 1 (Fgfr1) Proteins
fibroblast growth factor receptor 1 L homeolog (fgfr1.L) Proteins
fibroblast growth factor receptor 1a (fgfr1a) Proteins
ach Proteins
AW208770 Proteins
bFGF-R-1 Proteins
bfgfr Proteins
BFGFR Proteins
cb231 Proteins
cd331 Proteins
CD331 Proteins
cd333 Proteins
cek Proteins
CEK Proteins
cek2 Proteins
CG7223 Proteins
CT22273 Proteins
CT39172 Proteins
DFGF-R1 Proteins
DFGF-R2 Proteins
DFR-1 Proteins
Dfr-1 Proteins
DFR1 Proteins
Dfr1 Proteins
DFR1/DFGF-R2 Proteins
Dmel\\CG7223 Proteins
DmHD-38 Proteins
DPR3 Proteins
Dtk1 Proteins
dtk1 Proteins
DTRK(FR1) Proteins
Eask Proteins
EMS2 Proteins
FGF-R2 Proteins
fgfbr Proteins
FGFBR Proteins
FGFR Proteins
fgfr Proteins
fgfr-1 Proteins
FGFR-1 Proteins
Fgfr-1 Proteins
fgfr-3 Proteins
fgfr1 Proteins
FGFR2 Proteins
FGFRI Proteins
flg Proteins
FLG Proteins
FLG-1 Proteins
flt-2 Proteins
FLT-2 Proteins
Flt-2 Proteins
flt2 Proteins
FLT2 Proteins
FR1 Proteins
Fr1 Proteins
hbgfr Proteins
HBGFR Proteins
HD-38 Proteins
HH2 Proteins
hsfgfr3ex Proteins
Hspy Proteins
Htl Proteins
HTL/FGFR1 Proteins
i79 Proteins
i100 Proteins
i150 Proteins
j372 Proteins
jtk4 Proteins
kal2 Proteins
KAL2 Proteins
n-sam Proteins
N-SAM Proteins
ogd Proteins
OGD Proteins
sb:cb231 Proteins
Tk1 Proteins
X1FGFR Proteins
x1fgfr Proteins
XFGFR-1 Proteins
xfgfr1 Proteins
XFGFRA2 Proteins

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FGFR1 Proteins by Origin

FGFR1 Proteins by Source

FGFR1 Proteins by Protein Type

FGFR1 Proteins by Application

FGFR1 Proteins by Biological Activity

Popular FGFR1 Proteins

Latest Publications for our FGFR1 Proteins

Aliases for FGFR1 Proteins

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