FGF8 Products
(Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
Categories
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008].
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Featured FGF8 Categories
FGF8 Antibodies
High quality antibodies with extensive validation data.
FGF8 ELISA Kits
Reliable ELISA kits for a wide range of species.
FGF8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FGF8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (6)
Cat. No.
ABIN515614
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (2)
Cat. No.
ABIN672516
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1881345
Quantity
400 μL
Datasheet
Datasheet
Recommended FGF8 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955873
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962662
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955874
Quantity
96 tests
Datasheet
Datasheet
Recommended FGF8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (3)
Cat. No.
ABIN2017830
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5509905
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122948
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our FGF8 products
: "Sonic hedgehog protein regulates fibroblast growth factor 8 expression in metanephric explant culture from BALB/c mice: Possible mechanisms associated with renal morphogenesis." in: Molecular medicine reports, Vol. 14, Issue 4, pp. 2929-36, (2017) (PubMed).: "Mesenchymal stromal cell proliferation, gene expression and protein production in human platelet-rich plasma-supplemented media." in: PLoS ONE, Vol. 9, Issue 8, pp. e104662, (2014) (PubMed).
: "CMV-induced pathology: pathway and gene-gene interaction analysis." in: Experimental and molecular pathology, Vol. 97, Issue 1, pp. 154-65, (2014) (PubMed).
: "Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis." in: Hepatology (Baltimore, Md.), Vol. 53, Issue 3, pp. 854-64, (2011) (PubMed).
: "In vitro characterization of cardiac radiofrequency ablation lesions using optical coherence tomography." in: Optics express, Vol. 18, Issue 3, pp. 3079-92, (2010) (PubMed).
: "Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development." in: Developmental biology, Vol. 347, Issue 1, pp. 92-108, (2010) (PubMed).
: "FGF8 acts as a classic diffusible morphogen to pattern the neocortex." in: Development (Cambridge, England), Vol. 137, Issue 20, pp. 3439-48, (2010) (PubMed).
: "Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 239, Issue 9, pp. 2319-29, (2010) (PubMed).
: "BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation." in: Development (Cambridge, England), Vol. 137, Issue 18, pp. 3025-35, (2010) (PubMed).
: "Retinoid-suppressed phosphorylation of RARalpha mediates the differentiation pathway of osteosarcoma cells." in: Oncogene, Vol. 29, Issue 19, pp. 2772-83, (2010) (PubMed).
Synonyms and alternative names related to FGF8
fibroblast growth factor 8 (Fgf8), fibroblast growth factor 8 (FGF8), Aigf, AIGF, Fgf-8, FGF-8, HBGF-8, HH6, KAL6Protein level used designations for FGF8
- HBGF-8
- androgen-induced growth factor
- heparin-binding growth factor 8
- fibroblast growth factor 8 (androgen-induced)
- fibroblast growth factor 8
- fibroblast growth factor-8
- fibroblast growth factor 8 (androgen-induced) isoform 1
- fibroblast growth factor 8 (androgen-induced) isoform 2
- fibroblast growth factor 8 (androgen-induced) isoform 3
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