FGD4 Products
(FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
Categories
This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. [provided by RefSeq, Oct 2008].
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Featured FGD4 Categories
FGD4 Antibodies
High quality antibodies with extensive validation data.
FGD4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FGD4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p), ICC, IF
Validations
- (4)
Cat. No.
ABIN2856709
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN656907
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6140588
Quantity
100 μL
Datasheet
Datasheet
Recommended FGD4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3080181
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136852
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2721030
Quantity
20 μg
Datasheet
Datasheet
Synonyms and alternative names related to FGD4
FYVE, RhoGEF and PH domain containing 4 (FGD4), FYVE, RhoGEF and PH domain containing 4 (Fgd4), 9030023J02Rik, 9330209B17Rik, CMT4H, FRABP, Frabp, ZFYVE6Protein level used designations for FGD4
- FGD1 family, member 4
- FGD1-related F-actin-binding protein
- FYVE, RhoGEF and PH domain-containing protein 4
- actin-filament binding protein frabin
- zinc finger FYVE domain-containing protein 6
- Fgd1-related F-actin-binding protein
- actin filament-binding protein frabin
- frabin
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