FGD1 Products
(FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
Categories
This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.[provided by RefSeq, Mar 2011].
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Featured FGD1 Categories
FGD1 Antibodies
High quality antibodies with extensive validation data.
FGD1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FGD1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN7267284
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN2777407
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Pig, Rabbit
Application
WB
Validations
- (1)
Cat. No.
ABIN6737835
Quantity
100 μL
Datasheet
Datasheet
Recommended FGD1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092630
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3134432
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2721027
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our FGD1 products
: "MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice." in: The Journal of clinical investigation, Vol. 121, Issue 11, pp. 4383-92, (2011) (PubMed).Synonyms and alternative names related to FGD1
FYVE, RhoGEF and PH domain containing 1 (FGD1), FYVE, RhoGEF and PH domain containing 1 (Fgd1), FYVE, RhoGEF and PH domain containing 1 (fgd1), AAS, FGDY, MRXS16, ZFYVE3Protein level used designations for FGD1
- FYVE, RhoGEF and PH domain-containing protein 1
- faciogenital dysplasia 1 protein
- rho/Rac GEF
- rho/Rac guanine nucleotide exchange factor FGD1
- zinc finger FYVE domain-containing protein 3
- faciogenital dysplasia 1 protein homolog
- FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia)
- FYVE, RhoGEF and PH domain containing 1
- faciogenital dysplasia protein
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