FEZ1 Products
(Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))
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This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008].
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Featured FEZ1 Categories
FEZ1 Antibodies
High quality antibodies with extensive validation data.
FEZ1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FEZ1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN185737
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7152586
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (1)
Cat. No.
ABIN523131
Quantity
50 μg
Datasheet
Datasheet
Recommended FEZ1 Proteins
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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353974
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7424329
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3080240
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FEZ1 products
: "Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC." in: The EMBO journal, Vol. 31, Issue 8, pp. 1931-46, (2012) (PubMed).: "Interaction between FEZ1 and DISC1 in regulation of neuronal development and risk for schizophrenia." in: Neuron, Vol. 72, Issue 4, pp. 559-71, (2011) (PubMed).
: "Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt." in: Oncogene, Vol. 30, Issue 44, pp. 4487-97, (2011) (PubMed).
: "Two binding partners cooperate to activate the molecular motor Kinesin-1." in: The Journal of cell biology, Vol. 176, Issue 1, pp. 11-7, (2007) (PubMed).
: "Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules: role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation." in: The Journal of biological chemistry, Vol. 280, Issue 26, pp. 24948-56, (2005) (PubMed).
: "Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth." in: Molecular psychiatry, Vol. 8, Issue 7, pp. 685-94, (2003) (PubMed).
: "The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 7, pp. 3928-33, (1999) (PubMed).
: "Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein." in: The Journal of cell biology, Vol. 144, Issue 3, pp. 403-11, (1999) (PubMed).
: "The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 7, pp. 3414-9, (1997) (PubMed).
: "Structure and methylation-associated silencing of a gene within a homozygously deleted region of human chromosome band 8p22." in: Genomics, Vol. 35, Issue 1, pp. 55-65, (1996) (PubMed).
Synonyms and alternative names related to FEZ1
fasciculation and elongation protein zeta 1 (FEZ1), fasciculation and elongation protein zeta 1 (zygin I) (Fez1), fasciculation and elongation protein zeta 1 (Fez1), fasciculation and elongation protein zeta 1 (zygin I) (fez1), fasciculation and elongation protein zeta 1 L homeolog (fez1.L), fez1, UNC-76, UNC76, wu:fj14c12, xfez1, zgc:73258Protein level used designations for FEZ1
- fasciculation and elongation protein zeta-1
- zygin I
- zygin-1
- protein kinase C-binding protein Zeta1
- zygin 1
- fasciculation and elongation protein zeta 1 (zygin I)
- fasciculation and elongation protein zeta 1 L homeolog
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