FDFT1 Products
(Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))
Categories
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008].
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Featured FDFT1 Categories
FDFT1 Antibodies
High quality antibodies with extensive validation data.
FDFT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
FDFT1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FDFT1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7433993
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IF, IHC (p)
Validations
- (12)
Cat. No.
ABIN1498243
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (4)
Cat. No.
ABIN389052
Quantity
400 μL
Datasheet
Datasheet
Recommended FDFT1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593753
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Guinea Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN776835
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rabbit
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN774880
Quantity
96 tests
Datasheet
Datasheet
Recommended FDFT1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353932
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2129198
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7394720
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FDFT1 products
: "Mevalonate Biosynthesis Intermediates Are Key Regulators of Innate Immunity in Bovine Endometritis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 196, Issue 2, pp. 823-31, (2016) (PubMed).: "5-Aza-2'-deoxycytidine induced growth inhibition of leukemia cells through modulating endogenous cholesterol biosynthesis." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 7, pp. M111.016915, (2012) (PubMed).
: "Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches." in: Proteomics, Vol. 10, Issue 1, pp. 99-114, (2010) (PubMed).
: "Candidate serological biomarkers for cancer identified from the secretomes of 23 cancer cell lines and the human protein atlas." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 6, pp. 1100-17, (2010) (PubMed).
: "Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells." in: Lipids, Vol. 44, Issue 8, pp. 673-83, (2009) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonyms and alternative names related to FDFT1
farnesyl-diphosphate farnesyltransferase 1 (FDFT1), farnesyl-diphosphate farnesyltransferase 1 (fdft1), squalene synthase (LOC100560926), farnesyl diphosphate farnesyl transferase 1 (Fdft1), farnesyl-diphosphate farnesyltransferase 1 (Fdft1), DGPT, DKFZp459C1712, ERG9, FDFT1, fdft1, SQS, SSProtein level used designations for FDFT1
- farnesyl-diphosphate farnesyltransferase 1
- squalene synthase
- SS
- SQS
- Squalene synthetase
- FPP:FPP farnesyltransferase
- squalene synthase-like
- farnesyl-diphosphate farnesyltransferase
- squalene synthetase
- farnesyl diphosphate farnesyltransferase
- presqualene-di-diphosphate synthase
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