FCHO2 Products
(FCH Domain Only 2 (FCHO2))
Categories
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP- 2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
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Featured FCHO2 Categories
FCHO2 Antibodies
High quality antibodies with extensive validation data.
FCHO2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended FCHO2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7152394
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN1537842
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN1449925
Quantity
0.1 mg
Datasheet
Datasheet
Recommended FCHO2 ELISA Kits
Recommended FCHO2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092556
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135079
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FCHO2 products
: "A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation." in: eLife, Vol. 8, (2019) (PubMed).: "Endocytic proteins are partitioned at the edge of the clathrin lattice in mammalian cells." in: Nature cell biology, Vol. 19, Issue 4, pp. 352-361, (2017) (PubMed).
Synonyms and alternative names related to FCHO2
FCH domain only 2 (FCHO2), FCH domain only 2 (fcho2), FCH domain only 2 (Fcho2), 5832424M12Rik, AA387320, cb304, RGD1565396, sb:cb304, wu:fa01a02, zgc:112167Protein level used designations for FCHO2
- FCH domain only 2
- FCH domain only protein 2
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