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FBXW7 Proteins

(F-Box and WD Repeat Domain Containing 7 (FBXW7))

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class\; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].

recommended

FBXW7 Protein (AA 599-707) (GST tag) (ABIN1353879)

FBXW7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

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recommended

FBXW7 Protein (AA 1-553) (GST tag) (ABIN1990130)

FBXW7 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP

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recommended

FBXW7 Protein (AA 1-707) (Strep Tag) (ABIN3092548)

FBXW7 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant > 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

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FBXW7 Proteins by Origin

Find FBXW7 Proteins for a variety of species such as anti-Human FBXW7. The species listed below are among those available. Click on a link to go to the corresponding products.

FBXW7 Proteins by Source

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FBXW7 Proteins by Protein Type

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FBXW7 Proteins by Application

Find FBXW7 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular FBXW7 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

FBXW7 Protein (AA 599-707) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1353879

Quantity 10 μg

Datasheet Datasheet

FBXW7 Protein (AA 1-553) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1990130

Quantity 25 μg

Datasheet Datasheet

FBXW7 Protein (AA 1-707) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3092548

Quantity 1 mg

Datasheet Datasheet

Aliases for FBXW7 Proteins

F-box and WD repeat domain containing 7 (Fbxw7) Proteins
F-box and WD repeat domain containing 7 (FBXW7) Proteins
F-box and WD repeat domain containing 7 (fbxw7) Proteins
F-box and WD-40 domain protein 7 (Fbxw7) Proteins
1110001A17Rik Proteins
AGO Proteins
cdc4 Proteins
CDC4 Proteins
Cdc4 Proteins
FBW6 Proteins
FBW7 Proteins
Fbw7 Proteins
Fbwd6 Proteins
FBX30 Proteins
Fbx30 Proteins
FBXO30 Proteins
Fbxo30 Proteins
FBXW6 Proteins
Fbxw6 Proteins
hAgo Proteins
hCdc4 Proteins
SEL-10 Proteins
SEL10 Proteins

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FBXW7 Proteins by Origin

FBXW7 Proteins by Source

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FBXW7 Proteins by Application

Popular FBXW7 Proteins

Aliases for FBXW7 Proteins

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