FBXO4 Products
(F-Box Protein 4 (FBXO4))
Categories
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].
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Featured FBXO4 Categories
FBXO4 Antibodies
High quality antibodies with extensive validation data.
FBXO4 ELISA Kits
Reliable ELISA kits for a wide range of species.
FBXO4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FBXO4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC
Validations
- (4)
Cat. No.
ABIN7152437
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN525677
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7152439
Quantity
100 μg
Datasheet
Datasheet
Recommended FBXO4 ELISA Kits
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Reactivity
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Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774002
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN1743097
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Validations
Cat. No.
ABIN1769106
Quantity
96 tests
Datasheet
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Recommended FBXO4 Proteins
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Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353823
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3079809
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3126035
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FBXO4 products
: "Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins." in: Nature genetics, Vol. 46, Issue 6, pp. 588-94, (2014) (PubMed).: "PinX1 localizes to telomeres and stabilizes TRF1 at mitosis." in: Molecular and cellular biology, Vol. 32, Issue 8, pp. 1387-95, (2012) (PubMed).
: "Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛ" in: Oncogene, (2011) (PubMed).
: "Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability." in: Molecular and cellular biology, Vol. 28, Issue 23, pp. 7245-58, (2008) (PubMed).
: "Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer." in: Cancer cell, Vol. 14, Issue 1, pp. 68-78, (2008) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance." in: The Journal of biological chemistry, Vol. 281, Issue 2, pp. 759-68, (2006) (PubMed).
: "Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex." in: Molecular cell, Vol. 24, Issue 3, pp. 355-66, (2006) (PubMed).
: "The small heat-shock protein alpha B-crystallin promotes FBX4-dependent ubiquitination." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4699-704, (2003) (PubMed).
: "Induction of B cell costimulatory function by recombinant murine CD40 ligand." in: European journal of immunology, Vol. 24, Issue 1, pp. 116-23, (1994) (PubMed).
Synonyms and alternative names related to FBXO4
F-box protein 4 (FBXO4), F-box protein 4 (Fbxo4), F-box protein 4 (fbxo4), F-box protein 4 L homeolog (fbxo4.L), 1700096C12Rik, AI851261, AW494535, FBX4, Fbx4, fbx4, FBXO4, si:dkey-46a10.2Protein level used designations for FBXO4
- F-box only protein 4
- F-box protein Fbx4
- F-box protein 4
- F-box only protein 4-like
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