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F2RL3 Products

(Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008].

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Featured F2RL3 Categories

F2RL3 Antibodies

High quality antibodies with extensive validation data.

F2RL3 ELISA Kits

Reliable ELISA kits for a wide range of species.

F2RL3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended F2RL3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (7)
Cat. No. ABIN7431131
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN673224
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, FACS, ICC, LCI
Validations
  • (6)
Cat. No. ABIN7043077
Quantity 50 μL
Datasheet Datasheet

Recommended F2RL3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965883
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965882
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954861
Quantity 96 tests
Datasheet Datasheet

Recommended F2RL3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7491639
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
  • (1)
Cat. No. ABIN7538200
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353316
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our F2RL3 products

Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).

Muehlschlegel, Perry, Liu, Fox, Smith, Lichtner, Collard, Shernan, Hartwig, Body, Hoffmeister: "Polymorphism in the protease-activated receptor-4 gene region associates with platelet activation and perioperative myocardial injury." in: American journal of hematology, Vol. 87, Issue 2, pp. 161-6, (2013) (PubMed).

Getz, Dangelmaier, Jin, Daniel, Kunapuli: "Differential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets." in: Journal of thrombosis and haemostasis : JTH, Vol. 8, Issue 10, pp. 2283-93, (2010) (PubMed).

Akiyama, Carstens, Carstens: "Differential itch- and pain-related behavioral responses and µ-opoid modulation in mice." in: Acta dermato-venereologica, Vol. 90, Issue 6, pp. 575-81, (2010) (PubMed).

Weller, Dahl, Lohoff, Kampman, Oslin, Dackis, Ferraro, OBrien, Berrettini: "No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence." in: Psychiatric genetics, Vol. 16, Issue 5, pp. 193-6, (2006) (PubMed).

Gurumurthy, Goswami, Vasudevan, Rangnekar: "Phosphorylation of Par-4 by protein kinase A is critical for apoptosis." in: Molecular and cellular biology, Vol. 25, Issue 3, pp. 1146-61, (2005) (PubMed).

Xie, Guo: "Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28266-75, (2004) (PubMed).

Kukoc-Zivojnov, Puccetti, Chow, Bergmann, Ruthardt, Hoelzer, Mitrou, Weidmann, Boehrer: "Prostate apoptosis response gene-4 (par-4) abrogates the survival function of p185(BCR-ABL) in hematopoietic cells." in: Experimental hematology, Vol. 32, Issue 7, pp. 649-56, (2004) (PubMed).

Kahn, Nakanishi-Matsui, Shapiro, Ishihara, Coughlin: "Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin." in: The Journal of clinical investigation, Vol. 103, Issue 6, pp. 879-87, (1999) (PubMed).

Kahn, Hammes, Botka, Coughlin: "Gene and locus structure and chromosomal localization of the protease-activated receptor gene family." in: The Journal of biological chemistry, Vol. 273, Issue 36, pp. 23290-6, (1998) (PubMed).

Synonyms and alternative names related to F2RL3

F2R like thrombin or trypsin receptor 3 (F2RL3), F2R like thrombin/trypsin receptor 3 (F2RL3), coagulation factor II (thrombin) receptor-like 3 (F2rl3), F2R like thrombin or trypsin receptor 3 (F2rl3), F2RL3, PAR4

Protein level used designations for F2RL3

  • proteinase-activated receptor 4
  • coagulation factor II (thrombin) receptor-like 3
  • PAR-4
  • protease-activated receptor-4
  • thrombin receptor-like 3
  • coagulation factor II receptor-like 3
  • protease-activated receptor 4
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