F2RL1 Products
(Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
Categories
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008].
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Featured F2RL1 Categories
F2RL1 Antibodies
High quality antibodies with extensive validation data.
F2RL1 ELISA Kits
Reliable ELISA kits for a wide range of species.
F2RL1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended F2RL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN7043075
Quantity
25 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN7101760
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1049232
Quantity
50 μg
Datasheet
Datasheet
Recommended F2RL1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
- (1)
Cat. No.
ABIN6954858
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965879
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965880
Quantity
96 tests
Datasheet
Datasheet
Recommended F2RL1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491637
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122416
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353314
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our F2RL1 products
: "Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease-Activated Receptor-2, in Human Corneal Epithelial Cells." in: International journal of molecular sciences, Vol. 19, Issue 11, (2019) (PubMed).: "Structural insight into allosteric modulation of protease-activated receptor 2. ..." in: Nature, Vol. 545, Issue 7652, pp. 112-115, (2017) (PubMed).
: "Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells." in: European review for medical and pharmacological sciences, Vol. 20, Issue 22, pp. 4688-4696, (2017) (PubMed).
: "Epithelial Cell-Derived Cytokines Contribute to the Pathophysiology of Eosinophilic Chronic Rhinosinusitis." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 36, Issue 3, pp. 169-79, (2016) (PubMed).
: "Hydroxysafflor yellow A inhibits TGF-β1-induced activation of human fetal lung fibroblasts in vitro." in: The Journal of pharmacy and pharmacology, Vol. 68, Issue 10, pp. 1320-30, (2016) (PubMed).
: "Proteinase-activated receptor 2 and disease biomarkers in cerebrospinal fluid in cases with autopsy-confirmed prion diseases and other neurodegenerative diseases." in: BMC neurology, Vol. 15, pp. 50, (2015) (PubMed).
: "Cathepsin S, a new pruritus biomarker in clinical dandruff/seborrhoeic dermatitis evaluation." in: Experimental dermatology, Vol. 23, Issue 4, pp. 274-5, (2014) (PubMed).
: "PAR-2, IL-4R, TGF-? and TNF-? in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 533-538, (2014) (PubMed).
: "Biomarkers of fibroproliferative healing in fibrosing idiopathic interstitial pneumonias." in: The open respiratory medicine journal, Vol. 6, pp. 160-4, (2013) (PubMed).
: "Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).
Synonyms and alternative names related to F2RL1
Proteinase-activated receptor 2 (par2), F2R like trypsin receptor 1 (F2RL1), coagulation factor II (thrombin) receptor-like 1 (F2rl1), F2R like trypsin receptor 1 (F2rl1), Gpcr11, GPR11, PAR-2, Par-2, par2, PAR2, Par2Protein level used designations for F2RL1
- Proteinase-activated receptor 2
- G-protein coupled receptor 11
- coagulation factor II receptor-like 1
- protease-activated receptor 2
- proteinase-activated receptor 2
- thrombin receptor-like 1
- Protease-activated receptor-2
- proteinase-activated receptor-2
- Proteinase-activated receptor-2 G protein-coupled receptor 11
- Proteinase-activated receptor-2, G protein-coupled receptor 11
- PAR-2
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