F13A1 Products
(Coagulation Factor XIII, A1 Polypeptide (F13A1))
Categories
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits\; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008].
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Featured F13A1 Categories
F13A1 Antibodies
High quality antibodies with extensive validation data.
F13A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
F13A1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended F13A1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7433159
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (10)
Cat. No.
ABIN7442897
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7440509
Quantity
100 μL
Datasheet
Datasheet
Recommended F13A1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965912
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962106
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954886
Quantity
96 tests
Datasheet
Datasheet
Recommended F13A1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353305
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Human Cells
Validations
Cat. No.
ABIN7319648
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7393214
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our F13A1 products
: "Localized papular mucinosis with IgA nephropathy: a case report." in: Archives of dermatology, Vol. 147, Issue 5, pp. 599-602, (2011) (PubMed).: "Clinical significance of measuring blood coagulation factor XIIIA regularly and continuously in patients with Crohn's disease." in: Journal of gastroenterology and hepatology, Vol. 21, Issue 9, pp. 1407-11, (2006) (PubMed).
: "The coagulation cascade: initiation, maintenance, and regulation." in: Biochemistry, Vol. 30, Issue 43, pp. 10363-70, (1991) (PubMed).
Synonyms and alternative names related to F13A1
coagulation factor XIII A1 chain (F13a1), coagulation factor XIII, A1 polypeptide b (f13a1b), coagulation factor XIII A chain (F13A1), coagulation factor XIII, A1 subunit (F13a1), coagulation factor XIII A chain (F13a1), 1200014I03Rik, AI462306, F13a, F13A, f13a1, F13A1, wu:fo83d04, zgc:153334Protein level used designations for F13A1
- coagulation factor XIII A chain
- coagulation factor XIII, A1 subunit
- coagulation factor XIIIa
- protein-glutamine gamma-glutamyltransferase A chain
- transglutaminase A chain
- FX111a-87
- fo83d04
- coagulation factor XIII A1 subunit
- coagulation factor XIII, A1 polypeptide
- blood coagulation factor XIII A1 subunit
- coagulation factor XIIIA
- Coagulation factor XIII A chain
- FSF, A subunit
- TGase
- bA525O21.1 (coagulation factor XIII, A1 polypeptide)
- coagulation factor XIII, A polypeptide
- factor XIIIa
- fibrin stabilizing factor, A subunit
- fibrinoligase
- transglutaminase. plasma
- Factor XIIIA
- coagulation factor XIII, alpha subunit
- coagulation factor XIII A chain-like
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