F11R Products
(F11 Receptor (F11R))
Categories
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008].
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Featured F11R Categories
F11R Antibodies
High quality antibodies with extensive validation data.
F11R ELISA Kits
Reliable ELISA kits for a wide range of species.
F11R Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended F11R Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), PLA
Validations
- (4)
- (6)
Cat. No.
ABIN565503
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (1)
- (7)
Cat. No.
ABIN3021823
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (5)
Cat. No.
ABIN526357
Quantity
100 μL
Datasheet
Datasheet
Recommended F11R ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6955683
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966627
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1889392
Quantity
96 tests
Datasheet
Datasheet
Recommended F11R Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275080
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7092719
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7275081
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our F11R products
: "Enteropathogenic Escherichia coli (EPEC) Recruitment of PAR Polarity Protein Atypical PKCζ to Pedestals and Cell-Cell Contacts Precedes Disruption of Tight Junctions in Intestinal Epithelial Cells." in: International journal of molecular sciences, Vol. 21, Issue 2, (2020) (PubMed).: "Role of JAM-A tyrosine phosphorylation in epithelial barrier dysfunction during intestinal inflammation." in: Molecular biology of the cell, Vol. 30, Issue 5, pp. 566-578, (2019) (PubMed).
: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).
: "Early Detection of Junctional Adhesion Molecule-1 (JAM-1) in the Circulation after Experimental and Clinical Polytrauma." in: Mediators of inflammation, Vol. 2015, pp. 463950, (2015) (PubMed).
: "IL-18 Is Involved in Eosinophil-Mediated Tumoricidal Activity against a Colon Carcinoma Cell Line by Upregulating LFA-1 and ICAM-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 5, pp. 2483-92, (2015) (PubMed).
: "Low junctional adhesion molecule A expression correlates with poor prognosis in gastric cancer." in: The Journal of surgical research, Vol. 192, Issue 2, pp. 494-502, (2014) (PubMed).
: "Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury." in: Neurobiology of disease, Vol. 67, pp. 57-70, (2014) (PubMed).
: "Low expression of junctional adhesion molecule A is associated with metastasis and poor survival in pancreatic cancer." in: Annals of surgical oncology, Vol. 19, Issue 13, pp. 4330-6, (2012) (PubMed).
: "Relocalization of junctional adhesion molecule A during inflammatory stimulation of brain endothelial cells." in: Molecular and cellular biology, Vol. 32, Issue 17, pp. 3414-27, (2012) (PubMed).
: "Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma." in: Biochemical and biophysical research communications, Vol. 380, Issue 2, pp. 387-91, (2009) (PubMed).
Synonyms and alternative names related to F11R
F11 receptor (F11R), F11 receptor (F11r), 9130004G24, AA638916, CD321, ESTM33, JAM, JAM-1, JAM-A, JAM1, Jam1, JAMA, JCAM, Jcam, Jcam1, KAT, Ly106, PAM-1Protein level used designations for F11R
- junctional adhesion molecule 1
- junctional adhesion molecule A
- platelet F11 receptor
- platelet adhesion molecule 1
- BV11 antigen
- F11 receptor/F11R
- junction cell adhesion molecule A
- junction cell adhesion molecule1
- JAM-1
- JAM-A
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