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F-Box Protein 5 Products

(F-Box Protein 5 (FBXO5))
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1), which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Dec 2008].

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Featured F-Box Protein 5 Categories

F-Box Protein 5 Antibodies

High quality antibodies with extensive validation data.

F-Box Protein 5 ELISA Kits

Reliable ELISA kits for a wide range of species.

F-Box Protein 5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended F-Box Protein 5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, StM
Validations
  • (4)
Cat. No. ABIN6939501
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Pig, Rabbit
Application WB
Validations
  • (1)
  • (4)
Cat. No. ABIN2774700
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1538021
Quantity 400 μL
Datasheet Datasheet

Recommended F-Box Protein 5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743106
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1774011
Quantity 96 tests
Datasheet Datasheet
Reactivity Dog
Analytical Method
Validations
Cat. No. ABIN1769115
Quantity 96 tests
Datasheet Datasheet

Recommended F-Box Protein 5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353847
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3124183
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3080122
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our F-Box Protein 5 products

Marzio, Puccini, Kwon, Maverakis, Arbini, Sung, Bar-Sagi, Pagano: "The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers." in: Molecular cell, Vol. 73, Issue 2, pp. 224-237.e6, (2019) (PubMed).

Estrabaud, Le Rouzic, Lopez-Vergès, Morel, Belaïdouni, Benarous, Transy, Berlioz-Torrent, Margottin-Goguet: "Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles." in: PLoS pathogens, Vol. 3, Issue 7, pp. e104, (2007) (PubMed).

Synonyms and alternative names related to F-Box Protein 5

F-box protein 5 (FBXO5), F-box protein 5 (Fbxo5), F-box protein 5 (fbxo5), F-box only protein 5 (Fbxo5), F-box protein 5 L homeolog (fbxo5.L), F-box protein 5 S homeolog (fbxo5.S), 2510044I10Rik, ACYPI007854, C85305, EMI1, Emi1, emi1, FBX5, fbx5, Fbxo5, fbxo5, Fbxo31, fc65h02, wu:fc65h02, wu:fe06e07, wu:fz79f03, zgc:136397, zgc:158541

Protein level used designations for F-Box Protein 5

  • F-box only protein 5
  • F-box protein Fbx5
  • early mitotic inhibitor 1
  • f-box only protein 31
  • harpy
  • hrp
  • rca1
  • F-box only protein 5-B
  • early mitotic inhibitor 1-B
  • F-box only protein 5-A
  • early mitotic inhibitor 1-A
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