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FANCI Products

(Fanconi Anemia Complementation Group I (FANCI))

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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured FANCI Categories

FANCI Antibodies

High quality antibodies with extensive validation data.

FANCI ELISA Kits

Reliable ELISA kits for a wide range of species.

FANCI Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FANCI Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7152557
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6254031
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN1679817
Quantity 100 μg
Datasheet Datasheet

Recommended FANCI ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1132969
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132970
Quantity 96 tests
Datasheet Datasheet

Recommended FANCI Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353636
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092578
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136572
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our FANCI products

Colnaghi, Jones, Cotto-Rios, Schindler, Hanenberg, Huang: "Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair." in: Blood, Vol. 117, Issue 7, pp. 2247-56, (2011) (PubMed).

Yuan, El Hokayem, Zhou, Zhang: "FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24443-52, (2009) (PubMed).

Chu, Wang, Lu, Chou, Yang, Chang: "Involvement of p29 in DNA damage responses and Fanconi anemia pathway." in: Carcinogenesis, Vol. 30, Issue 10, pp. 1710-6, (2009) (PubMed).

Synonyms and alternative names related to FANCI

Fanconi anemia complementation group I (FANCI), Fanconi anemia, complementation group I (Fanci), KIAA1794

Protein level used designations for FANCI

  • Fanconi anemia group I protein
  • Fanconi anemia group I protein homolog
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