FANCA Products
(Fanconi Anemia Group A Protein (FANCA))
Categories
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008].
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Featured FANCA Categories
FANCA Antibodies
High quality antibodies with extensive validation data.
FANCA ELISA Kits
Reliable ELISA kits for a wide range of species.
FANCA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FANCA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN129606
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (3)
Cat. No.
ABIN2856901
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN515503
Quantity
50 μg
Datasheet
Datasheet
Recommended FANCA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966641
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1132955
Quantity
96 tests
Datasheet
Datasheet
Recommended FANCA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353621
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
Cat. No.
ABIN7317446
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092529
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our FANCA products
: "The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 6, pp. 2152-7, (2014) (PubMed).: "Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair." in: The EMBO journal, Vol. 31, Issue 17, pp. 3524-36, (2012) (PubMed).
: "RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network." in: The Journal of cell biology, Vol. 191, Issue 2, pp. 249-57, (2011) (PubMed).
: "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links." in: Molecular and cellular biology, Vol. 30, Issue 5, pp. 1217-30, (2010) (PubMed).
: "Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis." in: Molecular medicine (Cambridge, Mass.), Vol. 14, Issue 3-4, pp. 167-74, (2008) (PubMed).
: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).
: "Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30053-9, (2004) (PubMed).
Synonyms and alternative names related to FANCA
Fanconi anemia complementation group A (FANCA), Fanconi anemia, complementation group A (Fanca), AW208693, FA, FA-H, FA1, FAA, FACA, FAH, FANCHProtein level used designations for FANCA
- Fanconi anemia group A protein
- Fanconi anemia, complementation group H
- Fanconi anemia, type 1
- Fanconi anemia group A protein homolog
Did you look for something else?
- FAN1
- Family with Sequence Similarity 92, Member A1
- Family with Sequence Similarity 58, Member B
- Family with Sequence Similarity 50, Member A
- Family with Sequence Similarity 46, Member B
- Family with Sequence Similarity 220, Member A
- Family with Sequence Similarity 212, Member A
- Family with Sequence Similarity 102, Member B
- Family with Sequence Similarity 102, Member A
- FAM9C
- FAM9B
- FAM98C
- FAM98B
- FAM98A
- FAM96B
- FAM96A
- FAM92B
- FAM91A1
- Fam90a9
- Fam90a8
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