FAM84A Products
(Family with Sequence Similarity 84, Member A (FAM84A))
Categories
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.
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Featured FAM84A Categories
FAM84A Antibodies
High quality antibodies with extensive validation data.
FAM84A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended FAM84A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC (p)
Validations
- (4)
Cat. No.
ABIN566864
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
- (1)
- (2)
Cat. No.
ABIN1386304
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, WB, IHC
Validations
- (2)
Cat. No.
ABIN7248623
Quantity
200 μL
Datasheet
Datasheet
Recommended FAM84A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122885
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353598
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
Cat. No.
ABIN2727638
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our FAM84A products
: "Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 28, pp. 7864-9, (2016) (PubMed).: "Myocardin-related transcription factor-A is a key regulator in retinoic acid-induced neural-like differentiation of adult bone marrow-derived mesenchymal stem cells." in: Gene, Vol. 523, Issue 2, pp. 178-86, (2013) (PubMed).
Synonyms and alternative names related to FAM84A
family with sequence similarity 84, member A (Fam84a), family with sequence similarity 84 member A (FAM84A), family with sequence similarity 84, member A (fam84a), family with sequence similarity 84 member A (Fam84a), 2310003N02Rik, 4731402F03Rik, AW125753, Nse1, NSE1, PP11517, RGD1305779, zgc:63724Protein level used designations for FAM84A
- protein FAM84A
- neurologic sensory protein 1
- neurological/sensory 1
- family with sequence similarity 84, member A
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