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Factor XI Products

(Coagulation Factor XI (F11))

Categories

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008].

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Featured Factor XI Categories

Factor XI Antibodies

High quality antibodies with extensive validation data.

Factor XI ELISA Kits

Reliable ELISA kits for a wide range of species.

Factor XI Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Factor XI Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (4)
Cat. No. ABIN560828
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN947847
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7434170
Quantity 100 μL
Datasheet Datasheet

Recommended Factor XI ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965904
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965906
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965905
Quantity 96 tests
Datasheet Datasheet

Recommended Factor XI Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274693
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353293
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353295
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Factor XI products

Lewis, Suchindran, Beckman, Hooper, Grant, Heit, Manco-Johnson, Moll, Philipp, Kenney, De Staercke, Pyle, Chi, Ortel: "Whole blood gene expression profiles distinguish clinical phenotypes of venous thromboembolism." in: Thrombosis research, Vol. 135, Issue 4, pp. 659-65, (2015) (PubMed).

Synonyms and alternative names related to Factor XI

coagulation factor XI (F11), coagulation factor XI (CpipJ_CPIJ000593), coagulation factor XI (CpipJ_CPIJ001060), coagulation factor XI (CpipJ_CPIJ002752), coagulation factor XI (CpipJ_CPIJ003631), coagulation factor XI (CpipJ_CPIJ004041), coagulation factor XI (CpipJ_CPIJ004093), 1600027G01Rik, AI503996, Cf11, FXI, LRRGT00086

Protein level used designations for Factor XI

  • PTA
  • plasma thromboplastin antecedent
  • coagulation factor XI (plasma thromboplastin antecedent)
  • factor XI
  • platelet coagulation factor XI
  • blood coagulation factor XI
  • coagulation factor XI
  • coagulation factor XI-like
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