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Factor Xa Products

(Activated Coagulation Factor X (FXa))
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds\; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq, Jul 2008].

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Featured Factor Xa Categories

Factor Xa Antibodies

High quality antibodies with extensive validation data.

Factor Xa ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended Factor Xa Antibodies

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Reactivity
Application
Validations
Cat. No.
Quantity
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Reactivity Human
Application EIA, RIA
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Cat. No. ABIN613551
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Reactivity Human
Application EIA, RIA
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Cat. No. ABIN613081
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Recommended Factor Xa ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
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Cat. No. ABIN6973729
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6974599
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN770786
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our Factor Xa products

Yang, Su, Ren, Chen: "Synthesis of 3,4-diaminobenzoyl derivatives as factor Xa inhibitors." in: European journal of medicinal chemistry, Vol. 101, pp. 41-51, (2015) (PubMed).

Synonyms and alternative names related to Factor Xa

coagulation factor X (F10), FX, FXA

Protein level used designations for Factor Xa

  • Stuart-Prower factor
  • factor Xa
  • prothrombinase
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