Factor VIII Products
(Coagulation Factor VIII (F8))
Categories
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].
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Featured Factor VIII Categories
Factor VIII Antibodies
High quality antibodies with extensive validation data.
Factor VIII ELISA Kits
Reliable ELISA kits for a wide range of species.
Factor VIII Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Factor VIII Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7438070
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7434263
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7434266
Quantity
100 μL
Datasheet
Datasheet
Recommended Factor VIII ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6963573
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965897
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962842
Quantity
96 tests
Datasheet
Datasheet
Recommended Factor VIII Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353327
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353326
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7401242
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Factor VIII products
: "Local suture ligation-assisted percutaneous sclerotherapy for Kasabach-Merritt phenomenon-associated kaposiform haemangioendothelioma." in: Oncology letters, Vol. 17, Issue 1, pp. 981-989, (2019) (PubMed).: "Heparanase mediates vascular endothelial growth factor gene transcription in high-glucose human retinal microvascular endothelial cells." in: Molecular vision, Vol. 23, pp. 579-587, (2018) (PubMed).
: "Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43." in: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1847-1854, (2018) (PubMed).
: "Effects of preserving different veins on flow-through flap survival: An experimental study." in: Experimental and therapeutic medicine, Vol. 11, Issue 1, pp. 318-324, (2016) (PubMed).
: "A simple and biosafe method for isolation of human umbilical vein endothelial cells." in: Analytical biochemistry, Vol. 508, pp. 15-8, (2016) (PubMed).
: "The impact of minimally oversized adeno-associated viral vectors encoding human factor VIII on vector potency in vivo." in: Molecular therapy. Methods & clinical development, Vol. 3, pp. 16006, (2016) (PubMed).
: "Stereoselective Regulation of P-gp Activity by Clausenamide Enantiomers in Caco-2, KB/KBv and Brain Microvessel Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135866, (2016) (PubMed).
: "Effect of the Novel Biodegradable N, O-Carboxymethylchitosan and Oligo-Chitosan on the Platelet Thrombogenicity Cascade in von Willebrand Disease." in: Thrombosis research, Vol. 136, Issue 3, pp. 625-33, (2015) (PubMed).
: "Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-?B pathways." in: Scientific reports, Vol. 5, pp. 8209, (2015) (PubMed).
: "A ferulic acid (FA)-eluting system for biodegradable magnesium stent: Cells response of HUVECs." in: Journal of biomedical materials research. Part A, Vol. 103, Issue 8, pp. 2758-69, (2015) (PubMed).
Synonyms and alternative names related to Factor VIII
coagulation factor VIIi (f7i), coagulation factor VIII (F8), coagulation factor VIII, procoagulant component (F8), AHF, Cf-8, Cf8, DXS1253E, F8B, F8C, fb61d02, FVIII, HEMA, wu:fb61d02Protein level used designations for Factor VIII
- Factor VIII
- procoagulant component
- antihemophilic factor
- coagulation factor VIII
- coagulation factor VIIIc
- factor VIII F8B
- coagulation factor VIII, procoagulant component (hemophilia A)
- factor VIII
- coagulation co-factor
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