Exportin 2 Products
(CSE1 Chromosome Segregation 1-Like (CSE1L))
Categories
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
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Featured Exportin 2 Categories
Exportin 2 Antibodies
High quality antibodies with extensive validation data.
Exportin 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Exportin 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Exportin 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (11)
- (6)
Cat. No.
ABIN560494
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IF, IP, IHC (p), ICC
Validations
- (5)
Cat. No.
ABIN2855534
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC
Validations
- (3)
Cat. No.
ABIN7152321
Quantity
100 μL
Datasheet
Datasheet
Recommended Exportin 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955132
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1381055
Quantity
96 tests
Datasheet
Datasheet
Recommended Exportin 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350488
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350486
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3096357
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Exportin 2 products
: "The microRNA-451a/chromosome segregation 1-like axis suppresses cell proliferation, migration, and invasion and induces apoptosis in nasopharyngeal carcinoma." in: Bioengineered, Vol. 12, Issue 1, pp. 6967-6980, (2021) (PubMed).: "High expression of cytoplasmic phosphorylated CSE1L in malignant melanoma but not in benign nevi: phosphorylated CSE1L for the discrimination between melanoma and benign nevi." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1393-401, (2015) (PubMed).
: "Early decline in serum phospho-CSE1L levels in vemurafenib/sunitinib-treated melanoma and sorafenib/lapatinib-treated colorectal tumor xenografts." in: Journal of translational medicine, Vol. 13, pp. 191, (2015) (PubMed).
: "hCAS/CSE1L regulates RAD51 distribution and focus formation for homologous recombinational repair." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 9, pp. 681-94, (2015) (PubMed).
: "MIR-137 suppresses growth and invasion, is downregulated in oligodendroglial tumors and targets CSE1L." in: Brain pathology (Zurich, Switzerland), Vol. 23, Issue 4, pp. 426-39, (2013) (PubMed).
: "CSE1L modulates Ras-induced cancer cell invasion: correlation of K-Ras mutation and CSE1L expression in colorectal cancer progression." in: American journal of surgery, Vol. 206, Issue 3, pp. 418-27, (2013) (PubMed).
: "The prognostic significance of nuclear CSE1L in urinary bladder urothelial carcinomas." in: Annals of diagnostic pathology, Vol. 16, Issue 5, pp. 362-8, (2012) (PubMed).
: "Interaction of hydrogen sulfide and estrogen on the proliferation of vascular smooth muscle cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e41614, (2012) (PubMed).
: "Interdependency of cystathione ?-lyase and cystathione ?-synthase in hydrogen sulfide-induced blood pressure regulation in rats." in: American journal of hypertension, Vol. 25, Issue 1, pp. 74-81, (2011) (PubMed).
: "Differential distributions of CSE1L/CAS and E-cadherin in the polarized and non-polarized epithelial glands of neoplastic colorectal epithelium." in: Journal of molecular histology, Vol. 41, Issue 4-5, pp. 259-66, (2010) (PubMed).
Synonyms and alternative names related to Exportin 2
CAS/CSE1 segregation protein (Cas), chromosome segregation 1 like (CSE1L), exportin-2 (LOC100542094), chromosome segregation 1 like (cse1l), chromosome segregation 1-like (S. cerevisiae) (Cse1l), CSE1 chromosome segregation 1-like (yeast) (cse1l), CSE1 chromosome segregation 1-like L homeolog (cse1l.L), chromosome segregation 1 like (Cse1l), 2610100P18Rik, AA407533, BcDNA:LD14270, Capts, CAS, cas, Cas, CG13281, CSE1, CSE1L, Dcas, dcas, DKFZp459E1929, Dmel\\CG13281, Exportin-2, l(2)k03902, XPO2, Xpo2, xpo2Protein level used designations for Exportin 2
- CG13281-PA
- Cas-PA
- Importin-alpha re-exporter
- CSE1 chromosome segregation 1-like (yeast)
- CSE1 chromosome segregation 1-like protein
- CSE1 chromosome segregation 1-like
- exportin-2-like
- chromosome segregation 1-like protein
- exp2
- exportin-2
- importin-alpha re-exporter
- bao
- baobab
- cellular apoptosis susceptibilit
- cellular apoptosis susceptibility
- exportin 2
- cellular apoptosis susceptibility protein
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