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Exportin 2 Products

(CSE1 Chromosome Segregation 1-Like (CSE1L))

Categories

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

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Featured Exportin 2 Categories

Exportin 2 Antibodies

High quality antibodies with extensive validation data.

Exportin 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Exportin 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Exportin 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (11)
  • (6)
Cat. No. ABIN560494
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF, IP, IHC (p), ICC
Validations
  • (5)
Cat. No. ABIN2855534
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC
Validations
  • (3)
Cat. No. ABIN7152321
Quantity 100 μL
Datasheet Datasheet

Recommended Exportin 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955132
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381055
Quantity 96 tests
Datasheet Datasheet

Recommended Exportin 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350488
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350486
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3096357
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Exportin 2 products

Luo, Qu, Kan, Cai: "The microRNA-451a/chromosome segregation 1-like axis suppresses cell proliferation, migration, and invasion and induces apoptosis in nasopharyngeal carcinoma." in: Bioengineered, Vol. 12, Issue 1, pp. 6967-6980, (2021) (PubMed).

Chin, Wu, Shih, Yeh, Lee, Shen, Yeh, Jiang, Tseng: "High expression of cytoplasmic phosphorylated CSE1L in malignant melanoma but not in benign nevi: phosphorylated CSE1L for the discrimination between melanoma and benign nevi." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1393-401, (2015) (PubMed).

Lee, Shen, Shih, Chou, Tseng, Chin, Liu, Chen, Jiang: "Early decline in serum phospho-CSE1L levels in vemurafenib/sunitinib-treated melanoma and sorafenib/lapatinib-treated colorectal tumor xenografts." in: Journal of translational medicine, Vol. 13, pp. 191, (2015) (PubMed).

Okimoto, Sun, Fukuto, Horikoshi, Matsuda, Matsuda, Ikura, Ikura, Machida, Kurumizaka, Miyamoto, Oka, Yoneda, Kiuchi, Tashiro: "hCAS/CSE1L regulates RAD51 distribution and focus formation for homologous recombinational repair." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 9, pp. 681-94, (2015) (PubMed).

Li, Yang, Pang, Chan, Zhou, Mao, Wang, Lau, Poon, Shi, Ng: "MIR-137 suppresses growth and invasion, is downregulated in oligodendroglial tumors and targets CSE1L." in: Brain pathology (Zurich, Switzerland), Vol. 23, Issue 4, pp. 426-39, (2013) (PubMed).

Jiang, Yeh, Tai, Chen, Lin, Su, Shen, Lee, Liao, Li, Lee, Chen, Yeh, Chang: "CSE1L modulates Ras-induced cancer cell invasion: correlation of K-Ras mutation and CSE1L expression in colorectal cancer progression." in: American journal of surgery, Vol. 206, Issue 3, pp. 418-27, (2013) (PubMed).

Chang, Tai, Su, Shen, Lin, Yeh, Yeh, Lin, Jiang: "The prognostic significance of nuclear CSE1L in urinary bladder urothelial carcinomas." in: Annals of diagnostic pathology, Vol. 16, Issue 5, pp. 362-8, (2012) (PubMed).

Li, Mani, Cao, Yang, Lai, Wu, Wang: "Interaction of hydrogen sulfide and estrogen on the proliferation of vascular smooth muscle cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e41614, (2012) (PubMed).

Roy, Khan, Islam, Prieto, Majid: "Interdependency of cystathione ?-lyase and cystathione ?-synthase in hydrogen sulfide-induced blood pressure regulation in rats." in: American journal of hypertension, Vol. 25, Issue 1, pp. 74-81, (2011) (PubMed).

Uen, Tai, Shen, Lee, Tsao, Deng, Chiou, Hsu, Hsieh, Liao, Jiang: "Differential distributions of CSE1L/CAS and E-cadherin in the polarized and non-polarized epithelial glands of neoplastic colorectal epithelium." in: Journal of molecular histology, Vol. 41, Issue 4-5, pp. 259-66, (2010) (PubMed).

Synonyms and alternative names related to Exportin 2

CAS/CSE1 segregation protein (Cas), chromosome segregation 1 like (CSE1L), exportin-2 (LOC100542094), chromosome segregation 1 like (cse1l), chromosome segregation 1-like (S. cerevisiae) (Cse1l), CSE1 chromosome segregation 1-like (yeast) (cse1l), CSE1 chromosome segregation 1-like L homeolog (cse1l.L), chromosome segregation 1 like (Cse1l), 2610100P18Rik, AA407533, BcDNA:LD14270, Capts, CAS, cas, Cas, CG13281, CSE1, CSE1L, Dcas, dcas, DKFZp459E1929, Dmel\\CG13281, Exportin-2, l(2)k03902, XPO2, Xpo2, xpo2

Protein level used designations for Exportin 2

  • CG13281-PA
  • Cas-PA
  • Importin-alpha re-exporter
  • CSE1 chromosome segregation 1-like (yeast)
  • CSE1 chromosome segregation 1-like protein
  • CSE1 chromosome segregation 1-like
  • exportin-2-like
  • chromosome segregation 1-like protein
  • exp2
  • exportin-2
  • importin-alpha re-exporter
  • bao
  • baobab
  • cellular apoptosis susceptibilit
  • cellular apoptosis susceptibility
  • exportin 2
  • cellular apoptosis susceptibility protein
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