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Exonuclease 1 Products

(Exonuclease 1 (EXO1))

Categories

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008].

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Featured Exonuclease 1 Categories

Exonuclease 1 Antibodies

High quality antibodies with extensive validation data.

Exonuclease 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Exonuclease 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7152265
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (3)
Cat. No. ABIN6140356
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7444796
Quantity 100 μL
Datasheet Datasheet

Recommended Exonuclease 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN418163
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132644
Quantity 96 tests
Datasheet Datasheet

Recommended Exonuclease 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353210
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418920
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419106
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Exonuclease 1 products

Zahn, Eranki, Patenaude, Methot, Fifield, Cortizas, Foster, Imai, Durandy, Larijani, Verdun, Di Noia: "Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 11, pp. E988-97, (2014) (PubMed).

Cortizas, Zahn, Hajjar, Patenaude, Di Noia, Verdun: "Alternative end-joining and classical nonhomologous end-joining pathways repair different types of double-strand breaks during class-switch recombination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 11, pp. 5751-63, (2013) (PubMed).

Peterson, Li, Chait, Gottesman, Baer, Gautier: "Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair." in: The Journal of cell biology, Vol. 194, Issue 5, pp. 705-20, (2011) (PubMed).

Bolderson, Tomimatsu, Richard, Boucher, Kumar, Pandita, Burma, Khanna: "Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks." in: Nucleic acids research, Vol. 38, Issue 6, pp. 1821-31, (2010) (PubMed).

Genschel, Modrich: "Functions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch repair." in: The Journal of biological chemistry, Vol. 284, Issue 32, pp. 21536-44, (2009) (PubMed).

Bolderson, Richard, Edelmann, Khanna: "Involvement of Exo1b in DNA damage-induced apoptosis." in: Nucleic acids research, Vol. 37, Issue 10, pp. 3452-63, (2009) (PubMed).

Kim, Roh, Yoon, Kim, Park: "MLH3 and EXO1 alterations in familial colorectal cancer patients not fulfilling Amsterdam criteria." in: Cancer genetics and cytogenetics, Vol. 176, Issue 2, pp. 172-4, (2007) (PubMed).

Sharma, Sommers, Driscoll, Uzdilla, Wilson, Brosh: "The exonucleolytic and endonucleolytic cleavage activities of human exonuclease 1 are stimulated by an interaction with the carboxyl-terminal region of the Werner syndrome protein." in: The Journal of biological chemistry, Vol. 278, Issue 26, pp. 23487-96, (2003) (PubMed).

Synonyms and alternative names related to Exonuclease 1

exonuclease 1 (EXO1), hypothetical protein (Y17G7B.12), exonuclease I Exo1 (SJAG_01832), RNA exonuclease (PAS_chr1-1_0377), exonuclease 1 (Exo1), exonuclease 1 (exo1), exonuclease 1 S homeolog (exo1.S), exonuclease 1 (LOC100338764), 5730442G03Rik, EXO1, exoi, fc16e04, HEX1, hExoI, Msa, wu:fc16e04, zgc:55521

Protein level used designations for Exonuclease 1

  • hExo1
  • rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1
  • hypothetical protein
  • exonuclease I Exo1
  • RNA exonuclease
  • exonuclease I
  • mExo1
  • exonuclease 1
  • exonuclease ExoI
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