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EXOC2 Products

(Exocyst Complex Component 2 (EXOC2))

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The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].

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Featured EXOC2 Categories

EXOC2 Antibodies

High quality antibodies with extensive validation data.

Recommended EXOC2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6264959
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7152252
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7264281
Quantity 200 μL
Datasheet Datasheet

Recommended EXOC2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6204138
Quantity 96 tests
Datasheet Datasheet

Recommended EXOC2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092479
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137091
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our EXOC2 products

Simicek, Lievens, Laga, Guzenko, Aushev, Kalev, Baietti, Strelkov, Gevaert, Tavernier, Sablina: "The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response." in: Nature cell biology, Vol. 15, Issue 10, pp. 1220-30, (2013) (PubMed).

Synonyms and alternative names related to EXOC2

Secretory 5 (Sec5), exocyst complex component 2 (EXOC2), exocyst complex component 2 (Exoc2), exocyst complex component sec5 (SEC5A), Exocyst complex component 2 (sec-5), 2410030I24Rik, AI648199, CG8843, Dmel\\CG8843, dsec5, exocyst complex component sec5, F7O12.2, F7O12_2, Rsec5, Sec-5, Sec5, SEC5, SEC5L1, Sec5l1, Sec5p

Protein level used designations for EXOC2

  • CG8843-PA
  • sec5-PA
  • exocyst complex component 2
  • SEC5-like 1
  • exocyst complex component Sec5
  • SEC5 homolog
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