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Eukaryotic Translation Initiation Factor 4E Products

(Eukaryotic Translation Initiation Factor 4E (EIF4E))

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The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].

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Featured Eukaryotic Translation Initiation Factor 4E Categories

Eukaryotic Translation Initiation Factor 4E Antibodies

High quality antibodies with extensive validation data.

Eukaryotic Translation Initiation Factor 4E ELISA Kits

Reliable ELISA kits for a wide range of species.

Eukaryotic Translation Initiation Factor 4E Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Eukaryotic Translation Initiation Factor 4E Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (3)
  • (1)
Cat. No. ABIN1386772
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, FACS, ICC
Validations
  • (2)
  • (6)
Cat. No. ABIN969094
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (2)
  • (9)
Cat. No. ABIN3023085
Quantity 100 μL
Datasheet Datasheet

Recommended Eukaryotic Translation Initiation Factor 4E ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886047
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886050
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Cell ELISA
Validations
Cat. No. ABIN5526725
Quantity 96 tests
Datasheet Datasheet

Recommended Eukaryotic Translation Initiation Factor 4E Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1352595
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122850
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667809
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Eukaryotic Translation Initiation Factor 4E products

Dong, Chen, Chen, Wang, Cui, Tan, Robinson, Gao, Luo, Zhang, Zhao, Xiong, Mei: "CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation." in: Neuron, (2019) (PubMed).

Teng, Zhao, Gao, He, Li, Chen, Feng, Yi: "20(s)-Protopanaxadiol (PPD) increases the radiotherapy sensitivity of laryngeal carcinoma." in: Food & function, Vol. 8, Issue 12, pp. 4469-4477, (2018) (PubMed).

Yang, Hu, Fan, Zhang, Zhong, Guo, Qin, Chen: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).

Hu, Wang, Tang, Yang, Qin, Chen: "Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs." in: PLoS pathogens, Vol. 14, Issue 3, pp. e1006948, (2018) (PubMed).

Chen, Zhu, McCauley, Zhao, Johnson, Rhoads, El-Kadi: "Diminished satellite cell fusion and S6K1 expression in myotubes derived from skeletal muscle of low birth weight neonatal pigs." in: Physiological reports, Vol. 5, Issue 3, (2017) (PubMed).

Fletcher, Hill, Long, Gallagher, Shapiro, Rapp: "A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging." in: Neurobiology of learning and memory, Vol. 115, pp. 58-67, (2014) (PubMed).

Hoeffer, Santini, Ma, Arnold, Whelan, Wong, Pierre, Pelletier, Klann: "Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation." in: Journal of neurophysiology, Vol. 109, Issue 1, pp. 68-76, (2013) (PubMed).

Peruquetti, de Mateo, Sassone-Corsi: "Circadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e42695, (2012) (PubMed).

Hoeffer, Cowansage, Arnold, Banko, Moerke, Rodriguez, Schmidt, Klosi, Chorev, Lloyd, Pierre, Wagner, LeDoux, Klann: "Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 8, pp. 3383-8, (2011) (PubMed).

Andrieu, Taieb, Baylot, Ettinger, Soubeyran, De-Thonel, Nelson, Garrido, So, Fazli, Bladou, Gleave, Iovanna, Rocchi: "Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E." in: Oncogene, Vol. 29, Issue 13, pp. 1883-96, (2010) (PubMed).

Synonyms and alternative names related to Eukaryotic Translation Initiation Factor 4E

eukaryotic translation initiation factor 4E (EIF4E), eukaryotic translation initiation factor 4ea (eif4ea), eukaryotic translation initiation factor 4E (Eif4e), Eukaryotic initiation factor 4E (eIF-4E), eucaryotic initiation factor 6 (eif6), eukaryotic translation initiation factor 4E (eif4e), eukaryotic translation initiation factor 4E L homeolog (eif4e.L), eukaryotic translation initiation factor 4E family member 1B S homeolog (eif4e1b.S), translation initiation factor eIF4E (LOC100533326), eukaryotic translation initiation factor 4eb (eif4eb), 2, 0260/09, 0587/11, 0589/11, 0919/12, 1004/13, 7238, AUTS19, CBP, cbp, CG4035, CT13384, CT39424, CT39426, D-eIF4E, deIF-4E, dEif4e, deIF4E, Dmel\\CG4035, EG668879, eIF-4E, eIF-4e, eif-4E, eif-4e, EIF-4E, eIF-4E1, eIF-4E2, eIF-4EII, Eif4E, Eif4e, eIF 4E, eIF4E, eIF4e, eif4e, eif4e-1, eIF4E-1, eIF4E-1/2, eIF4E-2, Eif4e-ps, EIF4E1, eIF4E1, eif4e1, eIF4EI, EIF4EL1, eif4el1, EIF4F, eif4f, If4e, IF4E, l(3)07238, l(3)67Af, l(3)S025007, l(3)S026009, l(3)S058711, l(3)S091912, zgc:86680, zgc:101581

Protein level used designations for Eukaryotic Translation Initiation Factor 4E

  • eIF-4E
  • eIF-4F 25 kDa subunit
  • eukaryotic translation initiation factor 4E-like 1
  • mRNA cap-binding protein
  • eukaryotic translation initiation factor 4e 1a
  • eukaryotic translation initiation factor eIF4E-1
  • CG4035-PA
  • CG4035-PB
  • CG4035-PC
  • CG4035-PD
  • CG4035-PE
  • CG4035-PF
  • CG4035-PG
  • CG4035-PH
  • CG4035-PI
  • cap binding protein
  • eIF-4E-PA
  • eIF-4E-PB
  • eIF-4E-PC
  • eIF-4E-PD
  • eIF-4E-PE
  • eIF-4E-PF
  • eIF-4E-PG
  • eIF-4E-PH
  • eIF-4E-PI
  • eukaryotic initiation factor 4E
  • eukaryotic translation initiation factor 4E
  • lethal(3)67Af
  • eucaryotic initiation factor6
  • eIF4E
  • PCO081734
  • PCO081734_ov
  • eukaryotic translation initiation factor small subunit
  • elongation initiation factor 4E
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