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ETV4 Products

(Ets Variant 4 (ETV4))
Transcriptional activator that binds to the enhancer of the adenovirus E1A gene\; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.

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Featured ETV4 Categories

ETV4 Antibodies

High quality antibodies with extensive validation data.

ETV4 ELISA Kits

Reliable ELISA kits for a wide range of species.

ETV4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ETV4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (8)
  • (1)
Cat. No. ABIN6140332
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), FACS
Validations
  • (1)
  • (4)
Cat. No. ABIN390582
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN560805
Quantity 100 μg
Datasheet Datasheet

Recommended ETV4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648591
Quantity 96 tests
Datasheet Datasheet

Recommended ETV4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353183
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3079442
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3133565
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ETV4 products

Zhang, Yokoyama, Herriges, Zhang, Young, Verheyden, Sun: "E3 ubiquitin ligase RFWD2 controls lung branching through protein-level regulation of ETV transcription factors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 27, pp. 7557-62, (2017) (PubMed).

Kedage, Selvaraj, Nicholas, Budka, Plotnik, Jerde, Hollenhorst: "An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer." in: Cell reports, Vol. 17, Issue 5, pp. 1289-1301, (2016) (PubMed).

Okimoto, Breitenbuecher, Olivas, Wu, Gini, Hofree, Asthana, Hrustanovic, Flanagan, Tulpule, Blakely, Haringsma, Simmons, Gowen, Suh, Miller, Ali, Schuler, Bivona: "Inactivation of Capicua drives cancer metastasis." in: Nature genetics, Vol. 49, Issue 1, pp. 87-96, (2016) (PubMed).

Selvaraj, Budka, Ferris, Jerde, Hollenhorst: "Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation." in: Molecular cancer, Vol. 13, pp. 61, (2014) (PubMed).

Mesci, Taeb, Huang, Jairath, Sivaloganathan, Liu: "Pea3 expression promotes the invasive and metastatic potential of colorectal carcinoma." in: World journal of gastroenterology, Vol. 20, Issue 46, pp. 17376-87, (2014) (PubMed).

Pellecchia, Pescucci, De Lorenzo, Luceri, Passaro, Sica, Notaro, De Angioletti: "Overexpression of ETV4 is oncogenic in prostate cells through promotion of both cell proliferation and epithelial to mesenchymal transition." in: Oncogenesis, Vol. 1, pp. e20, (2013) (PubMed).

Zhang, Zhang, Gao, Wang, Liu: "Regulation of the microRNA 200b (miRNA-200b) by transcriptional regulators PEA3 and ELK-1 protein affects expression of Pin1 protein to control anoikis." in: The Journal of biological chemistry, Vol. 288, Issue 45, pp. 32742-52, (2013) (PubMed).

Wollenick, Hu, Kristiansen, Schraml, Rehrauer, Berchner-Pfannschmidt, Fandrey, Wenger, Stiehl: "Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling." in: Nucleic acids research, Vol. 40, Issue 5, pp. 1928-43, (2012) (PubMed).

Kampf, Bergman, Oksvold, Asplund, Navani, Wiking, Lundberg, Uhlén, Ponten: "A tool to facilitate clinical biomarker studies--a tissue dictionary based on the Human Protein Atlas." in: BMC medicine, Vol. 10, pp. 103, (2012) (PubMed).

Hollenhorst, Paul, Ferris, Graves: "The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells." in: Genes & cancer, Vol. 1, Issue 10, pp. 1044-1052, (2011) (PubMed).

Synonyms and alternative names related to ETV4

ETS variant 4 (ETV4), ets variant 4 (Etv4), ets variant 4 (etv4), AW414408, E1A-F, E1AF, Pea-3, PEA3, Pea3, pea3, PEAS3

Protein level used designations for ETV4

  • ETS translocation variant 4
  • EWS protein/E1A enhancer binding protein chimera
  • adenovirus E1A enhancer-binding protein
  • ets variant gene 4 (E1A enhancer-binding protein, E1AF)
  • polyomavirus enhancer activator 3 homolog
  • ets variant gene 4 (E1A enhancer binding protein, E1AF)
  • polyomavirus enhancer activator-3
  • ets domain protein
  • ETS variant protein 4
  • POLYOMAVIRUS ENHANCER ACTIVATOR 3 (PEA3 PROTEIN) (ETS TRANSLOCATION VARIANT 4)
  • ETS translocation variant 4-like
  • ETS domain-containing transcription factor PEA3
  • ETS-domain transcription factor pea3
  • etID309954.12
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