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Ets Variant 6 Products

(Ets Variant 6 (ETV6))
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008].

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Featured Ets Variant 6 Categories

Ets Variant 6 Antibodies

High quality antibodies with extensive validation data.

Ets Variant 6 ELISA Kits

Reliable ELISA kits for a wide range of species.

Ets Variant 6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Ets Variant 6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN560810
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP
Validations
  • (4)
Cat. No. ABIN3022303
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN5693220
Quantity 100 μg
Datasheet Datasheet

Recommended Ets Variant 6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966602
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648258
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648608
Quantity 96 tests
Datasheet Datasheet

Recommended Ets Variant 6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353187
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3079627
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3121159
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Ets Variant 6 products

Noetzli, Lo, Lee-Sherick, Callaghan, Noris, Savoia, Rajpurkar, Jones, Gowan, Balduini, Pecci, Gnan, De Rocco, Doubek, Li, Lu, Leung, Landolt-Marticorena, Hunger, Heller, Gutierrez-Hartmann, Xiayuan et al.: "Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia. ..." in: Nature genetics, Vol. 47, Issue 5, pp. 535-8, (2015) (PubMed).

Meester-Smoor, Janssen, ter Haar, van Wely, Aarnoudse, van Oord, van Tilburg, Zwarthoff: "The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation." in: PLoS ONE, Vol. 6, Issue 9, pp. e23620, (2011) (PubMed).

Van Vlierberghe, Ambesi-Impiombato, Perez-Garcia, Haydu, Rigo, Hadler, Tosello, Della Gatta, Paietta, Racevskis, Wiernik, Luger, Rowe, Rue, Ferrando: "ETV6 mutations in early immature human T cell leukemias." in: The Journal of experimental medicine, Vol. 208, Issue 13, pp. 2571-9, (2011) (PubMed).

Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).

Synonyms and alternative names related to Ets Variant 6

ETS variant 6 (etv6), ets variant 6 (Etv6), ETS variant 6 (ETV6), ets variant 6 (etv6), ETS variant 6 (Etv6), myosin, light chain 7, regulatory (myl7), AW123102, AW557856, cmlc2, etv-6, id:ibd2308, mylc2a, tel, Tel, TEL, tel/abl, TEL/ABL, zgc:92755

Protein level used designations for Ets Variant 6

  • TEL oncogene
  • ets variant gene 6 (TEL oncogene)
  • ETS translocation variant 6
  • ETS-related protein Tel1
  • transcription factor ETV6
  • translocation-ets-leukemia
  • ets domain protein
  • ztel
  • TEL1 oncogene
  • ets variant 6
  • cardiac myosin light chain 2
  • myosin light chain, regulatory A
  • myosin regulatory light chain 2, atrial isoform
  • myosin, light polypeptide 7, regulatory
  • tel
  • tell tale heart
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