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Espin Products

(Espin (ESPN))
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. [provided by RefSeq, Nov 2009].

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Featured Espin Categories

Espin Antibodies

High quality antibodies with extensive validation data.

Espin ELISA Kits

Reliable ELISA kits for a wide range of species.

Espin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Espin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN652258
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7267008
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7004857
Quantity 20 μL
Datasheet Datasheet

Recommended Espin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1132300
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132301
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1132302
Quantity 96 tests
Datasheet Datasheet

Recommended Espin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092462
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3137242
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2720520
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Espin products

Masuda, Nakamuta, Yamamoto: "Morphology of GNAT3-immunoreactive chemosensory cells in the rat larynx." in: Journal of anatomy, Vol. 234, Issue 2, pp. 149-164, (2019) (PubMed).

Hori, Koga, Kakizaki, Watanabe: "Differential effects of depot formulations of GnRH agonist leuprorelin and antagonist degarelix on the seminiferous epithelium of the rat testis." in: Biomedical research (Tokyo, Japan), Vol. 39, Issue 4, pp. 197-214, (2018) (PubMed).

Yu, Baird, Allen, Howe, Klassen, Reade, Makhijani, Song, Liu, Murthy, Zhang, Weiner, Kornberg, Jan, Davidson, Shu: "A naturally monomeric infrared fluorescent protein for protein labeling in vivo." in: Nature methods, Vol. 12, Issue 8, pp. 763-5, (2015) (PubMed).

Chen, Li, Wang, Wang, Zheng, Bartles: "Espin contains an additional actin-binding site in its N terminus and is a major actin-bundling protein of the Sertoli cell-spermatid ectoplasmic specialization junctional plaque." in: Molecular biology of the cell, Vol. 10, Issue 12, pp. 4327-39, (2000) (PubMed).

Bartles, Zheng, Li, Wierda, Chen: "Small espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli." in: The Journal of cell biology, Vol. 143, Issue 1, pp. 107-19, (1998) (PubMed).

Bartles, Wierda, Zheng: "Identification and characterization of espin, an actin-binding protein localized to the F-actin-rich junctional plaques of Sertoli cell ectoplasmic specializations." in: Journal of cell science, Vol. 109 ( Pt 6), pp. 1229-39, (1997) (PubMed).

Synonyms and alternative names related to Espin

espin (ESPN), espin (TVAG_100530), espin (LOAG_01035), espin (espn), espin (Espn), DFNB36, je, Je

Protein level used designations for Espin

  • espin
  • autosomal recessive deafness type 36 protein
  • ectoplasmic specialization protein
  • actin cytoskeletal regulatory protein
  • jerker
  • Jerker, deafness locus
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