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ERVW-1 Proteins

(Endogenous Retrovirus Group W, Member 1 (ERVW-1))

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010].

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ERVW-1 Protein (AA 116-215) (GST tag) (ABIN1353105)

ERVW-1 Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB

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ERVW-1 Proteins by Origin

Find ERVW-1 Proteins for a variety of species such as anti-Human ERVW-1. The species listed below are among those available. Click on a link to go to the corresponding products.

ERVW-1 Proteins by Source

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ERVW-1 Proteins by Protein Type

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ERVW-1 Proteins by Application

Find ERVW-1 Proteins validated for a specific application such as AP, AA, ELISA, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ERVW-1 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

ERVW-1 Protein (AA 116-215) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1353105

Quantity 10 μg

Datasheet Datasheet

Latest Publications for our ERVW-1 Proteins

Holder, Tower, Forbes, Mulla, Aplin, Abrahams: "Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1." in: Immunology, Vol. 136, Issue 2, pp. 184-91, (2012) (PubMed).

Aliases for ERVW-1 Proteins

endogenous retrovirus group W member 1, envelope (ERVW-1) Proteins
ENV Proteins
ENVW Proteins
ERVWE1 Proteins
HERV-7q Proteins
HERV-W-ENV Proteins
HERV7Q Proteins
HERVW Proteins
HERVWENV Proteins

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