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ERN2 Products

(Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.

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Featured ERN2 Categories

ERN2 Antibodies

High quality antibodies with extensive validation data.

ERN2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ERN2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ERN2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238930
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN391194
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN1533968
Quantity 100 μL
Datasheet Datasheet

Recommended ERN2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1157445
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1157446
Quantity 96 tests
Datasheet Datasheet

Recommended ERN2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508925
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421752
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ERN2 products

Iwawaki, Hosoda, Okuda, Kamigori, Nomura-Furuwatari, Kimata, Tsuru, Kohno: "Translational control by the ER transmembrane kinase/ribonuclease IRE1 under ER stress." in: Nature cell biology, Vol. 3, Issue 2, pp. 158-64, (2001) (PubMed).

Niwa, Sidrauski, Kaufman, Walter: "A role for presenilin-1 in nuclear accumulation of Ire1 fragments and induction of the mammalian unfolded protein response." in: Cell, Vol. 99, Issue 7, pp. 691-702, (2000) (PubMed).

Brewer, Diehl: "PERK mediates cell-cycle exit during the mammalian unfolded protein response." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 23, pp. 12625-30, (2000) (PubMed).

Synonyms and alternative names related to ERN2

endoplasmic reticulum to nucleus signaling 2 (ERN2), endoplasmic reticulum to nucleus signaling 2 (ern2), endoplasmic reticulum (ER) to nucleus signalling 2 (Ern2), endoplasmic reticulum to nucleus signaling 2 (Ern2), Ern1, Ire1, IRE1-BETA, ire1b, Ire1b, IRE1b, Ire1beta

Protein level used designations for ERN2

  • endoplasmic reticulum to nucleus signaling 2
  • endoplasmic reticulum to nucleus signalling 2
  • endoplasmic reticulum (ER) to nucleus signalling 2
  • endoplasmic reticulum-to-nucleus signaling 2
  • inositol-requiring 1 (Yeast homologue)
  • inositol-requiring 1 beta
  • inositol-requiring protein 2
  • ire1-beta
  • mIre1
  • serine/threonine-protein kinase/endoribonuclease IRE2
  • ER to nucleus signalling 2
  • IRE1 beta
  • IRE1, S. cerevisiae, homolog of
  • hIRE2p
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