ERN1 Products
(Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
Categories
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008].
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Featured ERN1 Categories
ERN1 Antibodies
High quality antibodies with extensive validation data.
ERN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ERN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ERN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (6)
Cat. No.
ABIN560791
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
- (3)
Cat. No.
ABIN969116
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN515393
Quantity
100 μg
Datasheet
Datasheet
Recommended ERN1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966485
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966484
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955549
Quantity
96 tests
Datasheet
Datasheet
Recommended ERN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353084
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1353082
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7317060
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ERN1 products
: "Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration." in: Scientific reports, Vol. 7, Issue 1, pp. 10220, (2019) (PubMed).: "Bladder cancer extracellular vesicles drive tumorigenesis by inducing the unfolded protein response in endoplasmic reticulum of nonmalignant cells." in: The Journal of biological chemistry, Vol. 294, Issue 9, pp. 3207-3218, (2019) (PubMed).
: "The serine/threonine-protein kinase/endoribonuclease IRE1α protects the heart against pressure overload-induced heart failure." in: The Journal of biological chemistry, Vol. 293, Issue 25, pp. 9652-9661, (2019) (PubMed).
: "ER-stress regulates macrophage polarization through pancreatic EIF-2alpha kinase." in: Cellular immunology, Vol. 336, pp. 40-47, (2019) (PubMed).
: "Nitrosative stress drives heart failure with preserved ejection fraction." in: Nature, Vol. 568, Issue 7752, pp. 351-356, (2019) (PubMed).
: "Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 5, pp. 662-676, (2019) (PubMed).
: "A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia." in: PLoS ONE, Vol. 14, Issue 4, pp. e0212235, (2019) (PubMed).
: "Myristate-induced endoplasmic reticulum stress requires ceramide synthases 5/6 and generation of C14-ceramide in intestinal epithelial cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 10, pp. 5724-5736, (2019) (PubMed).
: "Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy." in: Scientific reports, Vol. 7, Issue 1, pp. 6801, (2019) (PubMed).
: "The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity." in: Experimental & molecular medicine, Vol. 50, Issue 8, pp. 102, (2019) (PubMed).
Synonyms and alternative names related to ERN1
endoplasmic reticulum to nucleus signaling 1 (ERN1), endoplasmic reticulum to nucleus signaling 2 (ERN2), endoplasmic reticulum (ER) to nucleus signalling 1 (Ern1), endoplasmic reticulum to nucleus signaling 1 (Ern1), serine/threonine-protein kinase/endoribonuclease IRE1 (LOC524719), endoplasmic reticulum (ER) to nucleus signalling 2 (Ern2), endoplasmic reticulum to nucleus signaling 1 (ern1), 9030414B18Rik, AI225830, C85377, Ern1, hIRE1p, IRE1, Ire1, IRE1a, Ire1a, Ire1alpha, Ire1b, IRE1P, Ire1p, RGD1559716, sb:eu1005, zgc:109932Protein level used designations for ERN1
- ER to nucleus signalling 1
- endoplasmic reticulum-to-nucleus signaling 1
- inositol-requiring 1
- inositol-requiring enzyme 1
- inositol-requiring protein 1
- ire1-alpha
- protein kinase/endoribonuclease
- serine/threonine-protein kinase/endoribonuclease IRE1
- endoplasmic reticulum to nucleus signalling 1
- inositol-requiring 1 alpha
- endoplasmic reticulum (ER) to nucleus signalling 1
- endoplasmic reticulum-to-nucleus signaling 2
- inositol-requiring 1 (Yeast homologue)
- inositol-requiring 1 beta
- inositol-requiring protein 2
- ire1-beta
- mIre1
- serine/threonine-protein kinase/endoribonuclease IRE2
- endoplasmic reticulum to nucleus signaling 1
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