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ERCC6L Products

(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Categories

DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

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Featured ERCC6L Categories

ERCC6L Antibodies

High quality antibodies with extensive validation data.

ERCC6L Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ERCC6L Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
  • (3)
Cat. No. ABIN565778
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (6)
  • (2)
Cat. No. ABIN527207
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN527206
Quantity 100 μL
Datasheet Datasheet

Recommended ERCC6L ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6228431
Quantity 96 tests
Datasheet Datasheet

Recommended ERCC6L Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353041
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092403
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3136167
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ERCC6L products

Gemble, Buhagiar-Labarchède, Onclercq-Delic, Biard, Lambert, Amor-Guéret: "A balanced pyrimidine pool is required for optimal Chk1 activation to prevent ultrafine anaphase bridge formation." in: Journal of cell science, Vol. 129, Issue 16, pp. 3167-77, (2016) (PubMed).

Nera, Huang, Lai, Xu: "Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions." in: Nature communications, Vol. 6, pp. 10132, (2015) (PubMed).

Kang, Song, Du, Zhang, Liu, Liang, He, Lamb, Shen, Yin: "PTEN stabilizes TOP2A and regulates the DNA decatenation." in: Scientific reports, Vol. 5, pp. 17873, (2015) (PubMed).

Luebben, Kawabata, Johnson, OSullivan, Shima: "A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression." in: Nucleic acids research, Vol. 42, Issue 9, pp. 5605-15, (2014) (PubMed).

Rouzeau, Cordelières, Buhagiar-Labarchède, Hurbain, Onclercq-Delic, Gemble, Magnaghi-Jaulin, Jaulin, Amor-Guéret: "Bloom's syndrome and PICH helicases cooperate with topoisomerase II? in centromere disjunction before anaphase." in: PLoS ONE, Vol. 7, Issue 4, pp. e33905, (2012) (PubMed).

Muñoz, Laulier, Gunn, Cheng, Robbiani, Nussenzweig, Stark: "RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1." in: The Journal of biological chemistry, Vol. 287, Issue 48, pp. 40618-28, (2012) (PubMed).

Laulier, Cheng, Stark: "The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation." in: Nucleic acids research, Vol. 39, Issue 14, pp. 5935-44, (2011) (PubMed).

Kurasawa, Yu-Lee: "PICH and cotargeted Plk1 coordinately maintain prometaphase chromosome arm architecture." in: Molecular biology of the cell, Vol. 21, Issue 7, pp. 1188-99, (2010) (PubMed).

Leng, Bessuso, Jung, Wang, Qin: "Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 10, pp. 1480-9, (2008) (PubMed).

Synonyms and alternative names related to ERCC6L

ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), excision repair cross-complementing rodent repair deficiency complementation group 6 like (Ercc6l), ERCC excision repair 6 like, spindle assembly checkpoint helicase (Ercc6l), DNA excision repair protein ERCC-6-like (LOC100373376), DNA excision repair protein ERCC-6-like (LOC100494766), DNA excision repair protein ERCC-6-like (LOC100552957), DNA excision repair protein ERCC-6-like (LOC100560751), DNA excision repair protein ERCC-6-like (LOC100563247), excision repair cross-complementation group 6-like (ercc6l), BC004701, D330021P09Rik, fc22h03, PICH, RAD26L, RGD1565734, si:ch211-278b8.3, wu:fc22h03

Protein level used designations for ERCC6L

  • ATP-dependent helicase ERCC6-like
  • DNA excision repair protein ERCC-6-like
  • Plk1-interacting checkpoint helicase
  • SNF2/RAD54 family protein
  • excision repair cross-complementing rodent repair deficiency complementation group 6 - like
  • excision repair protein ERCC6-like
  • tumor antigen BJ-HCC-15
  • excision repair cross-complementing rodent repair deficiency complementation group 6-like
  • excision repair cross-complementing rodent repair deficiency, complementation group 6-like
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