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ERCC6 Products

(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

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This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544. [provided by RefSeq, Mar 2013].

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Featured ERCC6 Categories

ERCC6 Antibodies

High quality antibodies with extensive validation data.

ERCC6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ERCC6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IP, IHC (p), IF, ICC
Validations
  • (5)
Cat. No. ABIN2855858
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN654126
Quantity 400 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN2173875
Quantity 100 μL
Datasheet Datasheet

Recommended ERCC6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6214135
Quantity 96 tests
Datasheet Datasheet

Recommended ERCC6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353039
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3092380
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6239645
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our ERCC6 products

Aamann, Sorensen, Hvitby, Berquist, Muftuoglu, Tian, de Souza-Pinto, Scheibye-Knudsen, Wilson, Stevnsner, Bohr: "Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 7, pp. 2334-46, (2010) (PubMed).

Muftuoglu, de Souza-Pinto, Dogan, Aamann, Stevnsner, Rybanska, Kirkali, Dizdaroglu, Bohr: "Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase." in: The Journal of biological chemistry, Vol. 284, Issue 14, pp. 9270-9, (2009) (PubMed).

Synonyms and alternative names related to ERCC6

ERCC excision repair 6, chromatin remodeling factor (ERCC6), ERCC excision repair 6, chromatin remodeling factor (Ercc6), excision repair cross-complementing rodent repair deficiency, complementation group 6 (Ercc6), excision repair cross-complementation group 6 (ercc6), DNA excision repair protein ERCC-6 (LOC100719487), 4732403I04, ARMD5, C130058G22Rik, CKN2, COFS, COFS1, CSB, ercc6, Ercc6, RAD26, UVSS1

Protein level used designations for ERCC6

  • ATP-dependent helicase ERCC6
  • Cockayne syndrome group B protein
  • DNA excision repair protein ERCC-6
  • cockayne syndrome protein CSB
  • CS group B correcting
  • excision repair cross-complementing rodent repair deficiency, complementation group 6
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