ERCC5 Products
(DNA Repair Protein Complementing XP-G Cells (ERCC5))
Categories
This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011].
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Featured ERCC5 Categories
ERCC5 Antibodies
High quality antibodies with extensive validation data.
ERCC5 ELISA Kits
Reliable ELISA kits for a wide range of species.
ERCC5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ERCC5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (2)
Cat. No.
ABIN7434239
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6257134
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7300668
Quantity
100 μL
Datasheet
Datasheet
Recommended ERCC5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955423
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648051
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1130135
Quantity
96 tests
Datasheet
Datasheet
Recommended ERCC5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7395086
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3092497
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3133879
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ERCC5 products
: "Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin." in: mBio, Vol. 12, Issue 5, pp. e0122321, (2022) (PubMed).: "p300/CBP acetyl transferases interact with and acetylate the nucleotide excision repair factor XPG." in: DNA repair, Vol. 11, Issue 10, pp. 844-52, (2012) (PubMed).
: "Stem cell protein Piwil2 modulates chromatin modifications upon cisplatin treatment." in: Mutation research, Vol. 708, Issue 1-2, pp. 59-68, (2011) (PubMed).
Synonyms and alternative names related to ERCC5
ERCC excision repair 5, endonuclease (ERCC5), excision repair cross-complementation group 5 L homeolog (ercc5.L), excision repair cross-complementing rodent repair deficiency, complementation group 5 (Ercc5), ERCC excision repair 5, endonuclease (Ercc5), COFS3, cofs3, ERCM2, ercm2, UVDR, uvdr, XPG, xpg, Xpg, XPGC, xpgcProtein level used designations for ERCC5
- DNA repair protein complementing XP-G cells
- excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome))
- DNA excision repair protein ERCC-5
- XPG-complementing protein
- xeroderma pigmentosum, complementation group G
- DNA repair protein complementing XP-G cells homolog
- DNA-repair protein complementing XP-G cells homolog
- XP-G related factor
- xeroderma pigmentosum group G-complementing protein homolog
- XPG
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