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ER Lipid Raft Associated 2 Products

(ER Lipid Raft Associated 2 (ERLIN2))
This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].

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Featured ER Lipid Raft Associated 2 Categories

ER Lipid Raft Associated 2 Antibodies

High quality antibodies with extensive validation data.

ER Lipid Raft Associated 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ER Lipid Raft Associated 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ER Lipid Raft Associated 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (9)
Cat. No. ABIN7441649
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (4)
Cat. No. ABIN1537101
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7151997
Quantity 100 μL
Datasheet Datasheet

Recommended ER Lipid Raft Associated 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955634
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1132262
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1132263
Quantity 96 tests
Datasheet Datasheet

Recommended ER Lipid Raft Associated 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1353072
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2129121
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7409704
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ER Lipid Raft Associated 2 products

Zhang, Yao, Yu, Ni, Zhang, Wang, Lai: "Effects of 1.8 GHz radiofrequency radiation on protein expression in human lens epithelial cells." in: Human & experimental toxicology, Vol. 32, Issue 8, pp. 797-806, (2013) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Holland, Burleigh, Git, Goldgraben, Perez-Mancera, Chin, Hurtado, Bruna, Ali, Greenwood, Dunning, Samarajiwa, Menon, Rueda, Lynch, McKinney, Ellis, Eaves, Carroll, Curtis, Aparicio, Caldas: "ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium." in: EMBO molecular medicine, Vol. 3, Issue 3, pp. 167-80, (2011) (PubMed).

Jo, Sguigna, DeBose-Boyd: "Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase." in: The Journal of biological chemistry, Vol. 286, Issue 17, pp. 15022-31, (2011) (PubMed).

Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: "Tissue profiling of the mammalian central nervous system using human antibody-based proteomics." in: Molecular & cellular proteomics : MCP, Vol. 8, Issue 7, pp. 1612-22, (2009) (PubMed).

Pearce, Wang, Kelley, Wojcikiewicz: "SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells." in: The Journal of biological chemistry, Vol. 282, Issue 28, pp. 20104-15, (2007) (PubMed).

Garcia, Pole, Chin, Teschendorff, Naderi, Ozdag, Vias, Kranjac, Subkhankulova, Paish, Ellis, Brenton, Edwards, Caldas: "A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes." in: Oncogene, Vol. 24, Issue 33, pp. 5235-45, (2005) (PubMed).

Synonyms and alternative names related to ER Lipid Raft Associated 2

ER lipid raft associated 2 (ERLIN2), ER lipid raft associated 2 (erlin2), erlin-2 (Tsp_03442), Erlin-2 (erln2), ER lipid raft associated 2 (Erlin2), ER lipid raft associated 2 S homeolog (erlin2.S), ER lipid raft associated 2 L homeolog (erlin2.L), BC036333, C8orf2, C87251, Erlin-2, Erlin-2-B, erlin1, erlin2, erlin2-a, erlin2-b, NET32, RGD1309010, spfh1, SPFH2, Spfh2, spfh2, spfh2-A, spfh2-B, SPFH domain-containing protein 2-A, SPG18

Protein level used designations for ER Lipid Raft Associated 2

  • SPFH domain family, member 2
  • endoplasmic reticulum lipid raft-associated protein 2
  • erlin-2
  • stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
  • ER lipid raft associated 2
  • SPFH domain-containing protein 2
  • erlin-2-like
  • Erlin-2
  • ER lipid raft associated 1
  • Endoplasmic reticulum lipid raft-associated protein 2-B
  • SPFH domain-containing protein 2-B
  • Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-B
  • erlin-2-B
  • Endoplasmic reticulum lipid raft-associated protein 2-A
  • SPFH domain-containing protein 2-A
  • Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2-A
  • erlin-2-A
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