EPS15 Products
(Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
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This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009].
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Featured EPS15 Categories
EPS15 Antibodies
High quality antibodies with extensive validation data.
EPS15 ELISA Kits
Reliable ELISA kits for a wide range of species.
EPS15 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended EPS15 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN6140236
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6256811
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7244873
Quantity
200 μL
Datasheet
Datasheet
Recommended EPS15 ELISA Kits
Recommended EPS15 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2714444
Quantity
20 μg
Datasheet
Datasheet
Latest Publications for our EPS15 products
: "The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro." in: The Journal of cell biology, Vol. 154, Issue 6, pp. 1209-23, (2001) (PubMed).: "Regulation of complex formation of POB1/epsin/adaptor protein complex 2 by mitotic phosphorylation." in: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18399-406, (2000) (PubMed).
: "Solution structure of Eps15's third EH domain reveals coincident Phe-Trp and Asn-Pro-Phe binding sites." in: Biochemistry, Vol. 39, Issue 15, pp. 4309-19, (2000) (PubMed).
: "Molecular mechanism of NPF recognition by EH domains." in: Nature structural biology, Vol. 7, Issue 11, pp. 1018-22, (2000) (PubMed).
: "Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 16, pp. 8907-12, (1999) (PubMed).
: "Mapping of the molecular determinants involved in the interaction between eps15 and AP-2." in: Cancer research, Vol. 57, Issue 2, pp. 240-5, (1997) (PubMed).
: "Structural requirements of the epidermal growth factor receptor for tyrosine phosphorylation of eps8 and eps15, substrates lacking Src SH2 homology domains." in: The Journal of biological chemistry, Vol. 270, Issue 27, pp. 16271-6, (1995) (PubMed).
Synonyms and alternative names related to EPS15
epidermal growth factor receptor pathway substrate 15 (EPS15), Epidermal growth factor receptor pathway substrate clone 15 (Eps-15), epidermal growth factor receptor pathway substrate 15 (eps15), epidermal growth factor receptor pathway substrate 15 (Eps15), hypothetical protein (PGTG_06574), 2410112D09Rik, AF-1P, AF1P, anon-WO0118547.85, CG16932, Dmel\\CG16932, EH1, EPS-15, eps-15, Eps15, eps15, i31, MLLT5, RGD1307641Protein level used designations for EPS15
- ALL1 fused gene from chromosome 1
- epidermal growth factor receptor substrate 15
- protein AF-1p
- CG16932-PA
- CG16932-PB
- CG16932-PC
- CG16932-PD
- Eps-15-PA
- Eps-15-PB
- Eps-15-PC
- Eps-15-PD
- Eps15 homologue 1
- epidermal growth factor receptor pathway substrate clone 15
- epidermal growth factor receptor pathway substrate 15
- epidermal growth factor receptor substrate 15-like
- epidermal growth factor pathway substrate 15
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