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EPH Receptor B6 Products

(EPH Receptor B6 (EPHB6))
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands. [provided by RefSeq, Jul 2008].

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Featured EPH Receptor B6 Categories

EPH Receptor B6 Antibodies

High quality antibodies with extensive validation data.

EPH Receptor B6 ELISA Kits

Reliable ELISA kits for a wide range of species.

EPH Receptor B6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended EPH Receptor B6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN560773
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF, FACS
Validations
  • (5)
Cat. No. ABIN7013872
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7151870
Quantity 100 μg
Datasheet Datasheet

Recommended EPH Receptor B6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381115
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4886080
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882760
Quantity 96 tests
Datasheet Datasheet

Recommended EPH Receptor B6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1352947
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7195559
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7195560
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our EPH Receptor B6 products

Gu, Li, Qian, Chen, Wang, Wang: "Expression of EphB6 in ovarian serous carcinoma is associated with grade, TNM stage and survival." in: Journal of clinical pathology, (2015) (PubMed).

Bailey, Kulesa: "Dynamic interactions between cancer cells and the embryonic microenvironment regulate cell invasion and reveal EphB6 as a metastasis suppressor." in: Molecular cancer research : MCR, Vol. 12, Issue 9, pp. 1303-13, (2014) (PubMed).

Brantley-Sieders, Jiang, Sarma, Badu-Nkansah, Walter, Shyr, Chen: "Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome." in: PLoS ONE, Vol. 6, Issue 9, pp. e24426, (2011) (PubMed).

Islam, Loizides, Fialkovich, Grand, Montgomery: "Developmental expression of Eph and ephrin family genes in mammalian small intestine." in: Digestive diseases and sciences, Vol. 55, Issue 9, pp. 2478-88, (2010) (PubMed).

Lieben, Benn, Ajibade, Stockmans, Moermans, Hediger, Peng, Christakos, Bouillon, Carmeliet: "Trpv6 mediates intestinal calcium absorption during calcium restriction and contributes to bone homeostasis." in: Bone, Vol. 47, Issue 2, pp. 301-8, (2010) (PubMed).

Yu, Bulk, Ji, Hascher, Tang, Metzger, Marra, Serve, Berdel, Wiewroth, Koschmieder, Müller-Tidow: "The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2275-83, (2010) (PubMed).

Chou, Perez-Garcia, Kroll, OLeary: "Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex." in: Nature neuroscience, Vol. 12, Issue 11, pp. 1381-9, (2009) (PubMed).

Ogawa, Wada, Okada, Harada, Nakajima, Pasquale, Tsuyama: "EphB2 and ephrin-B1 expressed in the adult kidney regulate the cytoarchitecture of medullary tubule cells through Rho family GTPases." in: Journal of cell science, Vol. 119, Issue Pt 3, pp. 559-70, (2006) (PubMed).

Matsuoka, Obama, Kelly, Matsui, Nakamoto: "Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration." in: The Journal of biological chemistry, Vol. 280, Issue 32, pp. 29355-63, (2005) (PubMed).

Freywald, Sharfe, Rashotte, Grunberger, Roifman: "The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10150-6, (2003) (PubMed).

Synonyms and alternative names related to EPH Receptor B6

EPH receptor B6 (EPHB6), Eph receptor B6 (Ephb6), CEK9, Cekl, EPHB5, HEP, Mep

Protein level used designations for EPH Receptor B6

  • Chicken embryo kinase 9
  • EK9
  • EPH-like kinase 9
  • ephrin type-B receptor 5
  • ephrin receptor EphB6
  • ephrin type-B receptor 6
  • EPH receptor B6
  • ephrin type-B receptor 6-like
  • chicken eph/elk receptor-like protein
  • ephrin type A receptor
  • tyrosine-protein kinase-defective receptor EPH-6
  • human kinase-defective Eph-family receptor protein
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